Loading compound
Loading detail record from the SQLite release...
Compound
PGDB_C005340
4 activity records1 related patents
2D structure
CC(C)CC(CNC(=O)OC(C)(C)C)C(=O)NCc1ccc2c(c1)CN(C1CCC(=O)NC1=O)C2=OCompound summary
Physicochemical properties
Activity compounds and values
Activity records
| Structure | Control | Value | Concentration | Time | Record ID | Compound | Assay | Details | |||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| % Degradation | - | = | 80 | % | 10 uM | 24 h | GSPT1 | - | JeKo-1 | WO2023078410A1 | PGDB_A016595 | PGDB_C005340 | PGDB_AS000305 | View |
| IC50 | - | = | 32.7 | nM | - | — | GSPT1 | - | HNT-34 | WO2023078410A1 | PGDB_A025216 | PGDB_C005340 | PGDB_AS000001 | View |
| IC50 | - | = | 35.4 | nM | - | — | GSPT1 | - | HL-60 | WO2023078410A1 | PGDB_A031841 | PGDB_C005340 | PGDB_AS002047 | View |
| % Degradation | - | = | 52 | % | 100 nM | 24 h | GSPT1 | - | JeKo-1 | WO2023078410A1 | PGDB_A055186 | PGDB_C005340 | PGDB_AS002119 | View |