PatGlueDB | Molecular Glue Patent Bioactivity Database

Assay context summary

Assay context

38 activity records

Assay family% Degradation

Systemcell_based

Readout% Degradation

TargetGSPT1

E3Not specified

Cell lineMV-4-11

TechnologyWestern_blot

Detection targetprotein_degradation

Activity compounds and values

Activity records

38 records

Metric	Control	Relation	Value	Unit	Concentration	Time	Target	E3	Cell line	Patent	Record ID	Compound	Assay	Details
% Degradation	-	=	40-60	%	10 nM	6 h	GSPT1	-	MV-4-11	CN120289428A	PGDB_A007304	PGDB_C000715	PGDB_AS000838	View
% Degradation	-	=	40-60	%	10 nM	6 h	GSPT1	-	MV-4-11	CN120289428A	PGDB_A008966	PGDB_C000732	PGDB_AS000838	View
% Degradation	-	=	40-60	%	10 nM	6 h	GSPT1	-	MV-4-11	CN120289428A	PGDB_A009112	PGDB_C000702	PGDB_AS000838	View
% Degradation	-	=	60-80	%	10 nM	6 h	GSPT1	-	MV-4-11	CN120289428A	PGDB_A009231	PGDB_C000708	PGDB_AS000838	View
% Degradation	-	=	60-80	%	10 nM	6 h	GSPT1	-	MV-4-11	CN120289428A	PGDB_A009287	PGDB_C000711	PGDB_AS000838	View
% Degradation	-	=	40-60	%	10 nM	6 h	GSPT1	-	MV-4-11	CN120289428A	PGDB_A010308	PGDB_C000719	PGDB_AS000838	View
% Degradation	-	=	80-100	%	10 nM	6 h	GSPT1	-	MV-4-11	CN120289428A	PGDB_A011160	PGDB_C000700	PGDB_AS000838	View
% Degradation	-	=	60-80	%	10 nM	6 h	GSPT1	-	MV-4-11	CN120289428A	PGDB_A016068	PGDB_C000714	PGDB_AS000838	View
% Degradation	-	=	20-40	%	10 nM	6 h	GSPT1	-	MV-4-11	CN120289428A	PGDB_A019537	PGDB_C000733	PGDB_AS000838	View
% Degradation	-	=	40-60	%	10 nM	6 h	GSPT1	-	MV-4-11	CN120289428A	PGDB_A020379	PGDB_C000717	PGDB_AS000838	View
% Degradation	-	=	80-100	%	10 nM	6 h	GSPT1	-	MV-4-11	CN120289428A	PGDB_A030058	PGDB_C000727	PGDB_AS000838	View
% Degradation	-	=	60-80	%	10 nM	6 h	GSPT1	-	MV-4-11	CN120289428A	PGDB_A031714	PGDB_C000731	PGDB_AS000838	View
% Degradation	-	=	40-60	%	10 nM	6 h	GSPT1	-	MV-4-11	CN120289428A	PGDB_A032581	PGDB_C000709	PGDB_AS000838	View
% Degradation	-	=	20-40	%	10 nM	6 h	GSPT1	-	MV-4-11	CN120289428A	PGDB_A034170	PGDB_C000705	PGDB_AS000838	View
% Degradation	-	=	40-60	%	10 nM	6 h	GSPT1	-	MV-4-11	CN120289428A	PGDB_A036562	PGDB_C000723	PGDB_AS000838	View
% Degradation	-	=	40-60	%	10 nM	6 h	GSPT1	-	MV-4-11	CN120289428A	PGDB_A038886	PGDB_C000718	PGDB_AS000838	View
% Degradation	-	=	60-80	%	10 nM	6 h	GSPT1	-	MV-4-11	CN120289428A	PGDB_A040627	PGDB_C000058	PGDB_AS000838	View
% Degradation	-	=	60-80	%	10 nM	6 h	GSPT1	-	MV-4-11	CN120289428A	PGDB_A043460	PGDB_C000707	PGDB_AS000838	View
% Degradation	-	=	60-80	%	10 nM	6 h	GSPT1	-	MV-4-11	CN120289428A	PGDB_A047295	PGDB_C000722	PGDB_AS000838	View
% Degradation	-	=	80-100	%	10 nM	6 h	GSPT1	-	MV-4-11	CN120289428A	PGDB_A047701	PGDB_C000725	PGDB_AS000838	View

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