Assay

PGDB_AS001311

System: biochemicalTarget: CRBN | DDB1
Assay context summary

Assay context

17 activity records
Assay familybinding
Systembiochemical
ReadoutIC50
TargetCRBN | DDB1
E3CRBN | DDB1
Technologyfluorescence
Activity compounds and values

Activity records

17 records
StructureMetricControlRelationValueUnitConcentrationTimeTargetE3Cell linePatentRecord IDCompoundAssayDetails
2D structure for PGDB_C008996
IC50-=18.9uM-—CRBNCRBN-US12110292B2PGDB_A010797PGDB_C008996PGDB_AS001311View
2D structure for PGDB_C009001
IC50-=15.2uM-—CRBNCRBN-US12110292B2PGDB_A013564PGDB_C009001PGDB_AS001311View
2D structure for PGDB_C008994
IC50-=38.9uM-—CRBNCRBN-US12110292B2PGDB_A023526PGDB_C008994PGDB_AS001311View
2D structure for PGDB_C008989
IC50-=47.5uM-—CRBNCRBN-US12110292B2PGDB_A028459PGDB_C008989PGDB_AS001311View
2D structure for PGDB_C019024
IC50-=5.19uM-—CRBNCRBN-US12110292B2PGDB_A029425PGDB_C019024PGDB_AS001311View
2D structure for PGDB_C009002
IC50-=0.517uM-—CRBNCRBN-US12110292B2PGDB_A030212PGDB_C009002PGDB_AS001311View
2D structure for PGDB_C008998
IC50-=13.8uM-—CRBNCRBN-US12110292B2PGDB_A039151PGDB_C008998PGDB_AS001311View
2D structure for PGDB_C008991
IC50-=8.5uM-—CRBNCRBN-US12110292B2PGDB_A039587PGDB_C008991PGDB_AS001311View
2D structure for PGDB_C009003
IC50-=3.44uM-—CRBNCRBN-US12110292B2PGDB_A042505PGDB_C009003PGDB_AS001311View
2D structure for PGDB_C009000
IC50-=1.6uM-—CRBNCRBN-US12110292B2PGDB_A043169PGDB_C009000PGDB_AS001311View
2D structure for PGDB_C008999
IC50-=28.9uM-—CRBNCRBN-US12110292B2PGDB_A051524PGDB_C008999PGDB_AS001311View
2D structure for PGDB_C008993
IC50-=22.9uM-—CRBNCRBN-US12110292B2PGDB_A053389PGDB_C008993PGDB_AS001311View
2D structure for PGDB_C008992
IC50-=42.5uM-—CRBNCRBN-US12110292B2PGDB_A055588PGDB_C008992PGDB_AS001311View
2D structure for PGDB_C008988
IC50-=29.7uM-—CRBNCRBN-US12110292B2PGDB_A069671PGDB_C008988PGDB_AS001311View
2D structure for PGDB_C008997
IC50-=14.7uM-—CRBNCRBN-US12110292B2PGDB_A070312PGDB_C008997PGDB_AS001311View
2D structure for PGDB_C008990
IC50-=12.5uM-—CRBNCRBN-US12110292B2PGDB_A076330PGDB_C008990PGDB_AS001311View
2D structure for PGDB_C008995
IC50-=22.1uM-—CRBNCRBN-US12110292B2PGDB_A077620PGDB_C008995PGDB_AS001311View
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