Assay

PGDB_AS001330

System: cell_basedTarget: IKZF3Cell line: NCI-H929
Assay context summary

Assay context

2 activity records
Assay family% Degradation
Systemcell_based
Readout% Degradation
TargetIKZF3
E3CRBN
Cell lineNCI-H929
OrganismHomo sapiens
TechnologyWestern_blot
Detection targetprotein_degradation
Activity compounds and values

Activity records

2 records
StructureMetricControlRelationValueUnitConcentrationTimeTargetE3Cell linePatentRecord IDCompoundAssayDetails
2D structure for PGDB_C009602
% Degradation->25%20 uM24 hIKZF3CRBNNCI-H929WO2022146151A1PGDB_A041493PGDB_C009602PGDB_AS001330View
2D structure for PGDB_C009603
% Degradation->=75%20 uM24 hIKZF3CRBNNCI-H929WO2022146151A1PGDB_A052220PGDB_C009603PGDB_AS001330View
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