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Compound
PGDB_C023632
10 activity records1 related patents
2D structure
O=C1CCN(N2Cc3cc(CN4CC=C(c5ncnc6sc(-c7ccccc7)cc56)CC4)ccc3C2=O)C(=O)N1Compound summary
Physicochemical properties
Activity compounds and values
Activity records
| Structure | Control | Value | Concentration | Time | Record ID | Compound | Assay | Details | |||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| % Inhibition | - | = | 80-100 | % | 500 nM | - | - | - | MM.1S | WO2024245444A1 | PGDB_A007400 | PGDB_C023632 | PGDB_AS000503 | View |
| % Inhibition | - | = | 5-10 | % | 10 nM | - | - | - | H2228 | WO2024245444A1 | PGDB_A024543 | PGDB_C023632 | PGDB_AS001356 | View |
| % Inhibition | - | = | -5-0 | % | 10 nM | - | - | - | MM.1S | WO2024245444A1 | PGDB_A031340 | PGDB_C023632 | PGDB_AS001568 | View |
| % Inhibition | - | = | 60-80 | % | 500 nM | - | - | - | MDA-MB-231 | WO2024245444A1 | PGDB_A035157 | PGDB_C023632 | PGDB_AS002131 | View |
| % Inhibition | - | = | 80-100 | % | 500 nM | - | - | - | MV-4-11 | WO2024245444A1 | PGDB_A042178 | PGDB_C023632 | PGDB_AS000199 | View |
| % Inhibition | - | = | 10-18 | % | 10 nM | - | - | - | MV-4-11 | WO2024245444A1 | PGDB_A048280 | PGDB_C023632 | PGDB_AS001519 | View |
| % Inhibition | - | = | 40-60 | % | 500 nM | - | - | - | H2228 | WO2024245444A1 | PGDB_A060990 | PGDB_C023632 | PGDB_AS000051 | View |
| % Inhibition | - | = | 10-15 | % | 10 nM | - | - | - | MDA-MB-231 | WO2024245444A1 | PGDB_A067187 | PGDB_C023632 | PGDB_AS002156 | View |
| % Inhibition | - | = | 20-30 | % | 0.5 uM | 3 h | CRBN | CRBN | - | WO2024245444A1 | PGDB_A070854 | PGDB_C023632 | PGDB_AS001495 | View |
| % Inhibition | - | = | 53-60 | % | 2 uM | 3 h | CRBN | CRBN | - | WO2024245444A1 | PGDB_A074470 | PGDB_C023632 | PGDB_AS001510 | View |