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Compound
PGDB_C031230
5 activity records1 related patents
2D structure
COCc1cnc(C(C)(C)C(=O)NCc2cc(Cl)c(N3CCC(=O)NC3=O)c(Cl)c2)nc1Compound summary
Physicochemical properties
Activity compounds and values
Activity records
| Structure | Control | Value | Concentration | Time | Record ID | Compound | Assay | Details | |||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| EC50 | - | = | 3.4 | uM | - | — | CRBN | CRBN | - | WO2026099466A1 | PGDB_A001028 | PGDB_C031230 | PGDB_AS002171 | View |
| DC50 | - | = | 58 | nM | - | — | NEK7 | - | CAL-51 | WO2026099466A1 | PGDB_A006898 | PGDB_C031230 | PGDB_AS000897 | View |
| Dmax | - | = | 66 | % | Concentration series: 1 uM, 0.05 nM | - | NEK7 | - | CAL-51 | WO2026099466A1 | PGDB_A079365 | PGDB_C031230 | PGDB_AS000358 | View |
| IC50 | - | = | 0.1817 | uM | - | — | NEK7 | - | monocyte-derivedmacrophages | WO2026099466A1 | PGDB_A080346 | PGDB_C031230 | PGDB_AS001541 | View |
| IC50 | - | = | 0.2332 | uM | - | — | CASP1 | - | monocyte-derivedmacrophages | WO2026099466A1 | PGDB_A081320 | PGDB_C031230 | PGDB_AS002042 | View |