Assignee profile

H Lee Moffitt Cancer Center And Research Institute

Coverage of patents, compounds and activity records linked to this assignee.

2 patents85 compounds126 activity records
Summary
AssigneeH Lee Moffitt Cancer Center And Research Institute
Filing years2019-2025
Patents2
Compounds85
Activity records126
Patent families2
Targets3
Assay familiesbinding, biochemical, degradation
Activity metricsDC50, Dmax, IC50, Kd, degradation
Overview

Target distribution and active-compound trend

Target distribution

162 activity records

4 targets

Active compounds by publication year

Distinct compounds linked to assignee patent publications

0377420222025
Activity compounds and values

Activity records

162 records
Structure
Control
Value
ConcentrationTime
Record IDCompoundAssayDetails
2D structure for PGDB_C009092
% Inhibition-=46.7%-----US20220362229A1PGDB_A007419PGDB_C009092PGDB_AS001773View
2D structure for PGDB_C009131
% Degradation-=106.5%--CRBNCRBN-US20220362229A1PGDB_A008745PGDB_C009131PGDB_AS002247View
2D structure for PGDB_C009095
% Inhibition-=18.4%-----US20220362229A1PGDB_A009837PGDB_C009095PGDB_AS001773View
2D structure for PGDB_C009079
% Inhibition-=79.62%-----US20220362229A1PGDB_A009976PGDB_C009079PGDB_AS001773View
2D structure for PGDB_C009083
% Degradation-=91.11%--CRBNCRBN-US20220362229A1PGDB_A010031PGDB_C009083PGDB_AS002247View
2D structure for PGDB_C009070
% Inhibition-=18%-----US20220362229A1PGDB_A010497PGDB_C009070PGDB_AS001773View
2D structure for PGDB_C009123
Kd-=13.56uM-—CRBNCRBN-US20220362229A1PGDB_A011274PGDB_C009123PGDB_AS002291View
2D structure for PGDB_C009077
Kd-=11.15uM-—CRBNCRBN-US20220362229A1PGDB_A011461PGDB_C009077PGDB_AS002291View
2D structure for PGDB_C009099
% Degradation-=38.07%--CRBNCRBN-US20220362229A1PGDB_A011858PGDB_C009099PGDB_AS002247View
2D structure for PGDB_C009075
% Degradation-=36.53%--CRBNCRBN-US20220362229A1PGDB_A012112PGDB_C009075PGDB_AS002247View
2D structure for PGDB_C009065
% Degradation-=103.81%--CRBNCRBN-US20220362229A1PGDB_A012330PGDB_C009065PGDB_AS002247View
2D structure for PGDB_C009091
% Inhibition-=57.2%-----US20220362229A1PGDB_A012370PGDB_C009091PGDB_AS001773View
2D structure for PGDB_C009107
% Degradation-=82.18%--CRBNCRBN-US20220362229A1PGDB_A012496PGDB_C009107PGDB_AS002247View
2D structure for PGDB_C009088
Kd-=23.64uM-—CRBNCRBN-US20220362229A1PGDB_A013161PGDB_C009088PGDB_AS002291View
2D structure for PGDB_C009072
% Degradation-=6.19%--CRBNCRBN-US20220362229A1PGDB_A013324PGDB_C009072PGDB_AS002247View
2D structure for PGDB_C009096
Kd-=2.53uM-—CRBNCRBN-US20220362229A1PGDB_A013951PGDB_C009096PGDB_AS002291View
2D structure for PGDB_C009134
% Degradation-=153.23%--CRBNCRBN-US20220362229A1PGDB_A014073PGDB_C009134PGDB_AS002247View
2D structure for PGDB_C009084
Kd-=15.25uM-—CRBNCRBN-US20220362229A1PGDB_A015160PGDB_C009084PGDB_AS002291View
2D structure for PGDB_C009094
% Degradation-=9.54%--CRBNCRBN-US20220362229A1PGDB_A015499PGDB_C009094PGDB_AS002247View
2D structure for PGDB_C009118
% Degradation-=157.27%--CRBNCRBN-US20220362229A1PGDB_A016051PGDB_C009118PGDB_AS002247View
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