Summary
AssigneeHangzhou Zhongmei Huadong Pharmaceutical
Filing years2024-2025
Patents3
Compounds124
Activity records90
Patent families3
Targets2
Assay familiesselectivity, viability
Activity metricsinhibition, potency_ratio
Overview

Target distribution and active-compound trend

Target distribution

261 activity records

3 targets

Active compounds by publication year

Distinct compounds linked to assignee patent publications

0418220252026
Activity compounds and values

Activity records

261 records
Structure
Control
Value
ConcentrationTime
Record IDCompoundAssayDetails
2D structure for PGDB_C003418
% Inhibition-=12.86%--KCNH2-HEK293CN121449584APGDB_A025315PGDB_C003418PGDB_AS001701View
2D structure for PGDB_C003415
IC50-=41.25nM---MDA-MB-468CN121449584APGDB_A030869PGDB_C003415PGDB_AS002234View
2D structure for PGDB_C003418
% Inhibition-=10.41%--KCNH2-HEK293CN121449584APGDB_A031604PGDB_C003418PGDB_AS000243View
2D structure for PGDB_C003416
IC50-=6.385nM---NCI-H1155CN121449584APGDB_A033989PGDB_C003416PGDB_AS001856View
2D structure for PGDB_C003419
IC50-=2.839nM---NCI-H1155CN121449584APGDB_A034401PGDB_C003419PGDB_AS001856View
2D structure for PGDB_C003417
IC50-=9.845nM---NCI-H1155CN121449584APGDB_A041406PGDB_C003417PGDB_AS001856View
2D structure for PGDB_C003416
IC50-=27.82nM---MDA-MB-468CN121449584APGDB_A051768PGDB_C003416PGDB_AS002234View
2D structure for PGDB_C003417
IC50-=14.75nM---MDA-MB-468CN121449584APGDB_A054254PGDB_C003417PGDB_AS002234View
2D structure for PGDB_C003415
IC50-=12.82nM---NCI-H1155CN121449584APGDB_A068618PGDB_C003415PGDB_AS001856View
2D structure for PGDB_C003418
IC50-=9.571nM---MDA-MB-468CN121449584APGDB_A073709PGDB_C003418PGDB_AS002234View
2D structure for PGDB_C003418
IC50-=1.569nM---NCI-H1155CN121449584APGDB_A076979PGDB_C003418PGDB_AS001856View
2D structure for PGDB_C005413
Potency ratio-=0-1.3fold---NCI-H1155WO2025026218A1PGDB_A007489PGDB_C005413PGDB_AS001532View
2D structure for PGDB_C005388
% Inhibition-=37.69%--KCNH2-HEK293WO2025026218A1PGDB_A007639PGDB_C005388PGDB_AS000603View
2D structure for PGDB_C005410
Potency ratio-=1.3-2fold---MDA-MB-468WO2025026218A1PGDB_A008230PGDB_C005410PGDB_AS001889View
2D structure for PGDB_C005413
Potency ratio-=1.3-2fold---MDA-MB-468WO2025026218A1PGDB_A008669PGDB_C005413PGDB_AS001889View
2D structure for PGDB_C005427
% Inhibition-=60.74%--KCNH2-HEK293WO2025026218A1PGDB_A009294PGDB_C005427PGDB_AS000603View
2D structure for PGDB_C005374
Potency ratio-=2-10fold-GSPT1-GP2DWO2025026218A1PGDB_A009539PGDB_C005374PGDB_AS001306View
2D structure for PGDB_C005413
% Inhibition-=11.7%--KCNH2-HEK293WO2025026218A1PGDB_A009743PGDB_C005413PGDB_AS000603View
2D structure for PGDB_C005411
Potency ratio-=0-1.3fold---NCI-H1155WO2025026218A1PGDB_A009750PGDB_C005411PGDB_AS001532View
2D structure for PGDB_C005430
Potency ratio-=2-10fold---NCI-H1155WO2025026218A1PGDB_A010298PGDB_C005430PGDB_AS001532View