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Compound
PGDB_C000343
4 activity records1 related patents
2D structure
O=C1CCC(N2C(=O)c3cccc(N4CCN(CC5CN(C(=O)C(F)(F)c6ccc(Cl)cc6)C5)CC4)c3C2=O)C(=O)N1Compound summary
Physicochemical properties
Activity compounds and values
Activity records
| Structure | Control | Value | Concentration | Time | Record ID | Compound | Assay | Details | |||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| IC50 | - | = | 2000-4000 | nM | - | — | - | - | THP-1 | CN117683022A | PGDB_A008269 | PGDB_C000343 | PGDB_AS000289 | View |
| IC50 | - | = | 200-2000 | nM | - | — | - | - | Raji | CN117683022A | PGDB_A014595 | PGDB_C000343 | PGDB_AS000751 | View |
| % Degradation | - | = | 10-30 | % | 1 uM | - | GSPT1 | - | - | CN117683022A | PGDB_A033569 | PGDB_C000343 | PGDB_AS001783 | View |
| % Degradation | - | = | 10-30 | % | 1 uM | - | BRD4 | - | - | CN117683022A | PGDB_A045684 | PGDB_C000343 | PGDB_AS002272 | View |