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Compound
PGDB_C000354
4 activity records1 related patents
2D structure
O=C(/C=C/c1ccc(Cl)cc1)NCc1ccc2c(c1)CN(C1CCC(=O)NC1=O)C2=OCompound summary
Physicochemical properties
Activity compounds and values
Activity records
| Structure | Control | Value | Concentration | Time | Record ID | Compound | Assay | Details | |||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| % Degradation | - | = | 30-60 | % | 1 uM | - | BRD4 | - | - | CN117683022A | PGDB_A016873 | PGDB_C000354 | PGDB_AS002272 | View |
| % Degradation | - | = | 60-80 | % | 1 uM | - | GSPT1 | - | - | CN117683022A | PGDB_A031279 | PGDB_C000354 | PGDB_AS001783 | View |
| IC50 | - | = | 2000-4000 | nM | - | — | - | - | THP-1 | CN117683022A | PGDB_A036199 | PGDB_C000354 | PGDB_AS000289 | View |
| IC50 | - | < | 200 | nM | - | — | - | - | Raji | CN117683022A | PGDB_A073873 | PGDB_C000354 | PGDB_AS000751 | View |