Loading compound
Loading detail record from the SQLite release...
Compound
PGDB_C000972
10 activity records1 related patents
2D structure
CC1(C)CCC(C(=O)N2CCN(C3CCN(Cc4ccc5c(c4)CN(C4CCC(=O)NC4=O)C5=S)CC3(F)F)CC2)=C(c2ccc(Cl)cc2)C1Compound summary
Physicochemical properties
Activity compounds and values
Activity records
| Structure | Control | Value | Concentration | Time | Record ID | Compound | Assay | Details | |||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| % Inhibition | - | = | 50-60 | % | 0.1 uM | 24 h | IL1B | - | - | CN120548310A | PGDB_A014276 | PGDB_C000972 | PGDB_AS002470 | View |
| % Inhibition | - | = | 70-80 | % | 500 nM | 96 h | - | - | MM.1S | CN120548310A | PGDB_A030789 | PGDB_C000972 | PGDB_AS001316 | View |
| % Inhibition | - | = | 40-50 | % | 1 uM | 24 h | - | - | - | CN120548310A | PGDB_A036679 | PGDB_C000972 | PGDB_AS000296 | View |
| % Inhibition | - | <= | 10 | % | 0.1 uM | 24 h | - | - | - | CN120548310A | PGDB_A042698 | PGDB_C000972 | PGDB_AS001714 | View |
| % Inhibition | - | = | 80-90 | % | 1 uM | 24 h | - | - | - | CN120548310A | PGDB_A045190 | PGDB_C000972 | PGDB_AS000346 | View |
| % Inhibition | - | = | 60-70 | % | 0.1 uM | 24 h | - | - | - | CN120548310A | PGDB_A057172 | PGDB_C000972 | PGDB_AS000650 | View |
| % Inhibition | - | = | 80-90 | % | 1 uM | 24 h | - | - | - | CN120548310A | PGDB_A057918 | PGDB_C000972 | PGDB_AS001951 | View |
| % Inhibition | - | = | 70-80 | % | 2 uM | - | CRBN | CRBN | - | CN120548310A | PGDB_A063461 | PGDB_C000972 | PGDB_AS001462 | View |
| % Inhibition | - | = | 32-42 | % | 10 nM | 96 h | - | - | MM.1S | CN120548310A | PGDB_A065399 | PGDB_C000972 | PGDB_AS000332 | View |
| % Inhibition | - | = | 40-53 | % | 0.5 uM | - | CRBN | CRBN | - | CN120548310A | PGDB_A067185 | PGDB_C000972 | PGDB_AS002000 | View |