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Compound
PGDB_C001051
6 activity records1 related patents
2D structure
O=C1CCC(N2Cc3c(CCCCCN4CCC5(CC4)COc4c5cc(CO)nc4Cl)cccc3C2=O)C(=O)N1Compound summary
Physicochemical properties
Activity compounds and values
Activity records
| Structure | Control | Value | Concentration | Time | Record ID | Compound | Assay | Details | |||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Dmax | - | = | 60-80 | % | - | 16 h | IKZF1 | - | MV-4-11 | CN121471230A | PGDB_A017228 | PGDB_C001051 | PGDB_AS000264 | View |
| % Degradation | - | < | 25 | % | 1 uM | 16 h | GSPT1 | - | MV-4-11 | CN121471230A | PGDB_A029819 | PGDB_C001051 | PGDB_AS000062 | View |
| IC50 | - | < | 60 | nM | - | — | - | - | MV-4-11 | CN121471230A | PGDB_A035523 | PGDB_C001051 | PGDB_AS000948 | View |
| DC50 | - | = | 10-100 | nM | - | — | IKZF1 | - | MV-4-11 | CN121471230A | PGDB_A046206 | PGDB_C001051 | PGDB_AS000050 | View |
| DC50 | - | < | 10 | nM | - | — | CSNK1A1 | - | MV-4-11 | CN121471230A | PGDB_A046394 | PGDB_C001051 | PGDB_AS001026 | View |
| Dmax | - | > | 80 | % | - | 16 h | CSNK1A1 | - | MV-4-11 | CN121471230A | PGDB_A074061 | PGDB_C001051 | PGDB_AS001131 | View |