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Compound
PGDB_C001057
6 activity records1 related patents
2D structure
Cc1cc2c(cn1)OCC21CCN(CCCCCc2cccc3c2CN(C2CCC(=O)NC2=O)C3=O)CC1Compound summary
Physicochemical properties
Activity compounds and values
Activity records
| Structure | Control | Value | Concentration | Time | Record ID | Compound | Assay | Details | |||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Dmax | - | = | 60-80 | % | - | 16 h | IKZF1 | - | MV-4-11 | CN121471230A | PGDB_A007977 | PGDB_C001057 | PGDB_AS000264 | View |
| DC50 | - | = | 10-100 | nM | - | — | IKZF1 | - | MV-4-11 | CN121471230A | PGDB_A038568 | PGDB_C001057 | PGDB_AS000050 | View |
| IC50 | - | < | 60 | nM | - | — | - | - | MV-4-11 | CN121471230A | PGDB_A050446 | PGDB_C001057 | PGDB_AS000948 | View |
| % Degradation | - | < | 25 | % | 1 uM | 16 h | GSPT1 | - | MV-4-11 | CN121471230A | PGDB_A055000 | PGDB_C001057 | PGDB_AS000062 | View |
| Dmax | - | > | 80 | % | - | 16 h | CSNK1A1 | - | MV-4-11 | CN121471230A | PGDB_A065221 | PGDB_C001057 | PGDB_AS001131 | View |
| DC50 | - | < | 10 | nM | - | — | CSNK1A1 | - | MV-4-11 | CN121471230A | PGDB_A077879 | PGDB_C001057 | PGDB_AS001026 | View |