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Compound
PGDB_C001059
6 activity records1 related patents
2D structure
COc1cc2c(cn1)OCC21CCN(CCCCCc2cccc3c2CN(C2CCC(=O)NC2=O)C3=O)CC1Compound summary
Physicochemical properties
Activity compounds and values
Activity records
| Structure | Control | Value | Concentration | Time | Record ID | Compound | Assay | Details | |||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| % Degradation | - | < | 25 | % | - | 16 h | GSPT1 | - | MV-4-11 | CN121471230A | PGDB_A009860 | PGDB_C001059 | PGDB_AS000065 | View |
| DC50 | - | < | 10 | nM | - | — | CSNK1A1 | - | MV-4-11 | CN121471230A | PGDB_A011590 | PGDB_C001059 | PGDB_AS001026 | View |
| Dmax | - | > | 80 | % | - | 16 h | CSNK1A1 | - | MV-4-11 | CN121471230A | PGDB_A037273 | PGDB_C001059 | PGDB_AS001131 | View |
| DC50 | - | < | 10 | nM | - | — | IKZF1 | - | MV-4-11 | CN121471230A | PGDB_A052049 | PGDB_C001059 | PGDB_AS000050 | View |
| IC50 | - | < | 60 | nM | - | — | - | - | MV-4-11 | CN121471230A | PGDB_A059784 | PGDB_C001059 | PGDB_AS000948 | View |
| Dmax | - | = | 60-80 | % | - | 16 h | IKZF1 | - | MV-4-11 | CN121471230A | PGDB_A061478 | PGDB_C001059 | PGDB_AS000264 | View |