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Compound
PGDB_C001061
6 activity records1 related patents
2D structure
O=C1CCC(N2Cc3c(CCCCCN4CCC5(CC4)COc4cnc(C(F)(F)F)cc45)cc(F)cc3C2=O)C(=O)N1Compound summary
Physicochemical properties
Activity compounds and values
Activity records
| Structure | Control | Value | Concentration | Time | Record ID | Compound | Assay | Details | |||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| DC50 | - | < | 10 | nM | - | — | CSNK1A1 | - | MV-4-11 | CN121471230A | PGDB_A011335 | PGDB_C001061 | PGDB_AS001026 | View |
| % Degradation | - | < | 25 | % | - | 16 h | GSPT1 | - | MV-4-11 | CN121471230A | PGDB_A016575 | PGDB_C001061 | PGDB_AS000065 | View |
| Dmax | - | = | 60-80 | % | - | 16 h | IKZF1 | - | MV-4-11 | CN121471230A | PGDB_A043543 | PGDB_C001061 | PGDB_AS000264 | View |
| DC50 | - | = | 100-1000 | nM | - | — | IKZF1 | - | MV-4-11 | CN121471230A | PGDB_A044983 | PGDB_C001061 | PGDB_AS000050 | View |
| IC50 | - | < | 60 | nM | - | — | - | - | MV-4-11 | CN121471230A | PGDB_A045142 | PGDB_C001061 | PGDB_AS000948 | View |
| Dmax | - | > | 80 | % | - | 16 h | CSNK1A1 | - | MV-4-11 | CN121471230A | PGDB_A072720 | PGDB_C001061 | PGDB_AS001131 | View |