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CCN(C)S(=O)(=O)Nc1ccc(F)c(Oc2ccc3ncn([C@H]4[C@@H]5CN(c6ccc(C(=O)NC7CCN(c8ccc(NC9CCC(=O)NC9=O)cc8F)CC7)cc6)C[C@@H]54)c(=O)c3c2)c1C#N| Structure | Control | Value | Concentration | Time | Record ID | Compound | Assay | Details | |||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| DC50 | - | = | 6.82 | nM | - | — | BRAF | - | A375.10 | AU2022290851A1 | PGDB_A020500 | PGDB_C005688 | PGDB_AS001091 | View | |
| Emax | - | = | 13.56 | % | 10 uM | 24 h | BRAF | - | A375.10 | AU2022290851A1 | PGDB_A070732 | PGDB_C005688 | PGDB_AS000014 | View |