Assay

PGDB_AS001091

System: cell_basedCell line: A375.10
Assay context summary

Assay context

52 activity records
Assay family% Degradation
Systemcell_based
ReadoutDC50
E3Not specified
Cell lineA375.10
Technologyluminescence
Activity compounds and values

Activity records

52 records
StructureMetricControlRelationValueUnitConcentrationTimeTargetE3Cell linePatentRecord IDCompoundAssayDetails
2D structure for PGDB_C005706
DC50-=14.54nM-—BRAF-A375.10AU2022290851A1PGDB_A008195PGDB_C005706PGDB_AS001091View
2D structure for PGDB_C005714
DC50-=21.06nM-—BRAF-A375.10AU2022290851A1PGDB_A008754PGDB_C005714PGDB_AS001091View
2D structure for PGDB_C005689
DC50-=51.28nM-—BRAF-A375.10AU2022290851A1PGDB_A013075PGDB_C005689PGDB_AS001091View
2D structure for PGDB_C005724
DC50-=37.65nM-—BRAF-A375.10AU2022290851A1PGDB_A014244PGDB_C005724PGDB_AS001091View
2D structure for PGDB_C005730
DC50-=31.78nM-—BRAF-A375.10AU2022290851A1PGDB_A014744PGDB_C005730PGDB_AS001091View
2D structure for PGDB_C005691
DC50-=36.04nM-—BRAF-A375.10AU2022290851A1PGDB_A015390PGDB_C005691PGDB_AS001091View
2D structure for PGDB_C005735
DC50-=20.67nM-—BRAF-A375.10AU2022290851A1PGDB_A016871PGDB_C005735PGDB_AS001091View
2D structure for PGDB_C005711
DC50-=45.31nM-—BRAF-A375.10AU2022290851A1PGDB_A017409PGDB_C005711PGDB_AS001091View
2D structure for PGDB_C005725
DC50-=39.86nM-—BRAF-A375.10AU2022290851A1PGDB_A018256PGDB_C005725PGDB_AS001091View
2D structure for PGDB_C005690
DC50-=48.36nM-—BRAF-A375.10AU2022290851A1PGDB_A019995PGDB_C005690PGDB_AS001091View
2D structure for PGDB_C005688
DC50-=6.82nM-—BRAF-A375.10AU2022290851A1PGDB_A020500PGDB_C005688PGDB_AS001091View
2D structure for PGDB_C005738
DC50-=15.81nM-—BRAF-A375.10AU2022290851A1PGDB_A020534PGDB_C005738PGDB_AS001091View
2D structure for PGDB_C005710
DC50-=20.9nM-—BRAF-A375.10AU2022290851A1PGDB_A022947PGDB_C005710PGDB_AS001091View
2D structure for PGDB_C005703
DC50-=127.59nM-—BRAF-A375.10AU2022290851A1PGDB_A024550PGDB_C005703PGDB_AS001091View
2D structure for PGDB_C005720
DC50-=5.31nM-—BRAF-A375.10AU2022290851A1PGDB_A025090PGDB_C005720PGDB_AS001091View
2D structure for PGDB_C005733
DC50-=30.51nM-—BRAF-A375.10AU2022290851A1PGDB_A027689PGDB_C005733PGDB_AS001091View
2D structure for PGDB_C005697
DC50-=25.14nM-—BRAF-A375.10AU2022290851A1PGDB_A029519PGDB_C005697PGDB_AS001091View
2D structure for PGDB_C005731
DC50-=49.67nM-—BRAF-A375.10AU2022290851A1PGDB_A029869PGDB_C005731PGDB_AS001091View
2D structure for PGDB_C005729
DC50-=50.11nM-—BRAF-A375.10AU2022290851A1PGDB_A030122PGDB_C005729PGDB_AS001091View
2D structure for PGDB_C005693
DC50-=8.13nM-—BRAF-A375.10AU2022290851A1PGDB_A031837PGDB_C005693PGDB_AS001091View
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