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CCN(C)S(=O)(=O)Nc1ccc(F)c(Oc2ccc3ncn(C4CCC5(CCN(C(=O)CN6CCC(c7ccc(NC8CCC(=O)NC8=O)cc7F)CC6)CC5)C4)c(=O)c3c2C)c1C#N| Structure | Control | Value | Concentration | Time | Record ID | Compound | Assay | Details | |||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| DC50 | - | = | 20.9 | nM | - | — | BRAF | - | A375.10 | AU2022290851A1 | PGDB_A022947 | PGDB_C005710 | PGDB_AS001091 | View | |
| Emax | - | = | 11.5 | % | 10 uM | 24 h | BRAF | - | A375.10 | AU2022290851A1 | PGDB_A048008 | PGDB_C005710 | PGDB_AS000014 | View |