Loading compound
Loading detail record from the SQLite release...
Compound
PGDB_C005735
2 activity records1 related patents
2D structure
CCN(C)S(=O)(=O)Nc1ccc(F)c(Nc2ccc3ncn([C@H]4COC5(CCN(C(=O)CN6CCC(c7ccc(NC8CCC(=O)NC8=O)cc7F)CC6)CC5)C4)c(=O)c3c2)c1C#NCompound summary
Physicochemical properties
Activity compounds and values
Activity records
| Structure | Control | Value | Concentration | Time | Record ID | Compound | Assay | Details | |||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| DC50 | - | = | 20.67 | nM | - | — | BRAF | - | A375.10 | AU2022290851A1 | PGDB_A016871 | PGDB_C005735 | PGDB_AS001091 | View |
| Emax | - | = | 6.45 | % | 10 uM | 24 h | BRAF | - | A375.10 | AU2022290851A1 | PGDB_A042610 | PGDB_C005735 | PGDB_AS000014 | View |