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CCS(=O)(=O)Nc1ccc(F)c(Oc2ccc3ncn(-c4ccc(N5CCN(C(=O)CN6CCC(c7c(F)cc(NC8CCC(=O)NC8=O)cc7OC)CC6)CC5)nc4)c(=O)c3c2)c1C#N| Structure | Control | Value | Concentration | Time | Record ID | Compound | Assay | Details | |||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Emax | - | = | 10.07 | % | 10 uM | 24 h | BRAF | - | A375.10 | AU2022290851A1 | PGDB_A010573 | PGDB_C005740 | PGDB_AS001074 | View | |
| DC50 | - | = | 30.33 | nM | - | — | BRAF | - | A375.10 | AU2022290851A1 | PGDB_A069256 | PGDB_C005740 | PGDB_AS001629 | View |