Assay

PGDB_AS001629

System: cell_basedTarget: BRAFCell line: A375.10
Assay context summary

Assay context

58 activity records
Assay family% Degradation
Systemcell_based
ReadoutDC50
TargetBRAF
E3Not specified
Cell lineA375.10
Technologyluminescence
Activity compounds and values

Activity records

58 records
StructureMetricControlRelationValueUnitConcentrationTimeTargetE3Cell linePatentRecord IDCompoundAssayDetails
2D structure for PGDB_C005741
DC50-=15.14nM-—BRAF-A375.10AU2022290851A1PGDB_A008458PGDB_C005741PGDB_AS001629View
2D structure for PGDB_C005755
DC50-=48.26nM-—BRAF-A375.10AU2022290851A1PGDB_A012348PGDB_C005755PGDB_AS001629View
2D structure for PGDB_C005743
DC50-=23.46nM-—BRAF-A375.10AU2022290851A1PGDB_A013210PGDB_C005743PGDB_AS001629View
2D structure for PGDB_C005748
DC50-=10.71nM-—BRAF-A375.10AU2022290851A1PGDB_A013744PGDB_C005748PGDB_AS001629View
2D structure for PGDB_C005776
DC50-=15.68nM-—BRAF-A375.10AU2022290851A1PGDB_A014966PGDB_C005776PGDB_AS001629View
2D structure for PGDB_C005770
DC50-=18.74nM-—BRAF-A375.10AU2022290851A1PGDB_A015202PGDB_C005770PGDB_AS001629View
2D structure for PGDB_C005754
DC50-=15.01nM-—BRAF-A375.10AU2022290851A1PGDB_A015529PGDB_C005754PGDB_AS001629View
2D structure for PGDB_C005783
DC50-=14.55nM-—BRAF-A375.10AU2022290851A1PGDB_A016110PGDB_C005783PGDB_AS001629View
2D structure for PGDB_C005780
DC50-=19.51nM-—BRAF-A375.10AU2022290851A1PGDB_A017648PGDB_C005780PGDB_AS001629View
2D structure for PGDB_C005775
DC50-=50.66nM-—BRAF-A375.10AU2022290851A1PGDB_A018122PGDB_C005775PGDB_AS001629View
2D structure for PGDB_C005788
DC50-=34.19nM-—BRAF-A375.10AU2022290851A1PGDB_A018588PGDB_C005788PGDB_AS001629View
2D structure for PGDB_C005745
DC50-=8.71nM-—BRAF-A375.10AU2022290851A1PGDB_A021159PGDB_C005745PGDB_AS001629View
2D structure for PGDB_C005763
DC50-=18.62nM-—BRAF-A375.10AU2022290851A1PGDB_A023197PGDB_C005763PGDB_AS001629View
2D structure for PGDB_C005783
DC50-=7.26nM-—BRAF-A375.10AU2022290851A1PGDB_A024643PGDB_C005783PGDB_AS001629View
2D structure for PGDB_C005795
DC50-=242nM-—BRAF-A375.10AU2022290851A1PGDB_A027930PGDB_C005795PGDB_AS001629View
2D structure for PGDB_C005777
DC50-=15.65nM-—BRAF-A375.10AU2022290851A1PGDB_A029208PGDB_C005777PGDB_AS001629View
2D structure for PGDB_C005794
DC50-=165nM-—BRAF-A375.10AU2022290851A1PGDB_A029798PGDB_C005794PGDB_AS001629View
2D structure for PGDB_C005782
DC50-=16.51nM-—BRAF-A375.10AU2022290851A1PGDB_A030662PGDB_C005782PGDB_AS001629View
2D structure for PGDB_C005792
DC50-=55.04nM-—BRAF-A375.10AU2022290851A1PGDB_A032839PGDB_C005792PGDB_AS001629View
2D structure for PGDB_C005744
DC50-=42.44nM-—BRAF-A375.10AU2022290851A1PGDB_A032852PGDB_C005744PGDB_AS001629View
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