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Compound
PGDB_C005754
4 activity records1 related patents
2D structure
CCN(C)S(=O)(=O)Nc1ccc(F)c(Oc2ccc3ncn(-c4cnc(N5CCN(C(=O)CN6CCC(c7ccc(N[C@@H]8CCC(=O)NC8=O)cc7F)CC6)CC5)nc4)c(=O)c3c2N)c1C#NCompound summary
Physicochemical properties
Activity compounds and values
Activity records
| Structure | Control | Value | Concentration | Time | Record ID | Compound | Assay | Details | |||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| DC50 | - | = | 15.01 | nM | - | — | BRAF | - | A375.10 | AU2022290851A1 | PGDB_A015529 | PGDB_C005754 | PGDB_AS001629 | View |
| Emax | - | = | 11.62 | % | 10 uM | 24 h | BRAF | - | A375.10 | AU2022290851A1 | PGDB_A058485 | PGDB_C005754 | PGDB_AS001074 | View |
| Emax | - | = | 9.75 | % | 10 uM | 24 h | BRAF | - | A375.10 | AU2022290851A1 | PGDB_A061602 | PGDB_C005754 | PGDB_AS001074 | View |
| DC50 | - | = | 27.67 | nM | - | — | BRAF | - | A375.10 | AU2022290851A1 | PGDB_A072983 | PGDB_C005754 | PGDB_AS001629 | View |