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Compound
PGDB_C005783
4 activity records1 related patents
2D structure
CCN(C)S(=O)(=O)Nc1ccc(F)c(Oc2ccc3ncn([C@H]4COC5(CCN([C@H]6CC[C@@H](c7ccc(NC8CCC(=O)NC8=O)cc7F)CC6)CC5)C4)c(=O)c3c2)c1C#NCompound summary
Physicochemical properties
Activity compounds and values
Activity records
| Structure | Control | Value | Concentration | Time | Record ID | Compound | Assay | Details | |||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| DC50 | - | = | 14.55 | nM | - | — | BRAF | - | A375.10 | AU2022290851A1 | PGDB_A016110 | PGDB_C005783 | PGDB_AS001629 | View |
| Emax | - | = | 8.05 | % | 10 uM | 24 h | BRAF | - | A375.10 | AU2022290851A1 | PGDB_A019970 | PGDB_C005783 | PGDB_AS001074 | View |
| DC50 | - | = | 7.26 | nM | - | — | BRAF | - | A375.10 | AU2022290851A1 | PGDB_A024643 | PGDB_C005783 | PGDB_AS001629 | View |
| Emax | - | = | 8.5 | % | 10 uM | 24 h | BRAF | - | A375.10 | AU2022290851A1 | PGDB_A025852 | PGDB_C005783 | PGDB_AS001074 | View |