Loading compound
Loading detail record from the SQLite release...
Compound
PGDB_C005847
2 activity records1 related patents
2D structure
Cn1nc(N2CCC(=O)NC2=O)c2cc(F)c(N3CCC(O)(CC(=O)N4CCC5(CC4)C[C@@H](n4cnc6ccc(Oc7c(F)ccc(NS(=O)(=O)N8CCC8)c7C#N)cc6c4=O)CO5)CC3)cc21Compound summary
Physicochemical properties
Activity compounds and values
Activity records
| Structure | Control | Value | Concentration | Time | Record ID | Compound | Assay | Details | |||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Emax | - | = | 89.38 | % | 10 uM | 24 h | BRAF | - | A375.10 | AU2022290851A1 | PGDB_A016029 | PGDB_C005847 | PGDB_AS000362 | View |
| DC50 | - | = | 9990 | nM | - | — | BRAF | - | A375.10 | AU2022290851A1 | PGDB_A055581 | PGDB_C005847 | PGDB_AS001308 | View |