Assay

PGDB_AS000362

System: cell_basedTarget: BRAFCell line: A375.10
Assay context summary

Assay context

61 activity records
Assay family% Degradation
Systemcell_based
ReadoutEmax
TargetBRAF
E3Not specified
Cell lineA375.10
Technologyluminescence
Activity compounds and values

Activity records

61 records
StructureMetricControlRelationValueUnitConcentrationTimeTargetE3Cell linePatentRecord IDCompoundAssayDetails
2D structure for PGDB_C005805
Emax-=14.2%10 uM24 hBRAF-A375.10AU2022290851A1PGDB_A007249PGDB_C005805PGDB_AS000362View
2D structure for PGDB_C005850
Emax-=27.85%10 uM24 hBRAF-A375.10AU2022290851A1PGDB_A007760PGDB_C005850PGDB_AS000362View
2D structure for PGDB_C005809
Emax-=30%10 uM24 hBRAF-A375.10AU2022290851A1PGDB_A008407PGDB_C005809PGDB_AS000362View
2D structure for PGDB_C005813
Emax-=14.52%10 uM24 hBRAF-A375.10AU2022290851A1PGDB_A009235PGDB_C005813PGDB_AS000362View
2D structure for PGDB_C005824
Emax-=46.03%10 uM24 hBRAF-A375.10AU2022290851A1PGDB_A010683PGDB_C005824PGDB_AS000362View
2D structure for PGDB_C005854
Emax-=11.27%10 uM24 hBRAF-A375.10AU2022290851A1PGDB_A011288PGDB_C005854PGDB_AS000362View
2D structure for PGDB_C005812
Emax-=20.72%10 uM24 hBRAF-A375.10AU2022290851A1PGDB_A013586PGDB_C005812PGDB_AS000362View
2D structure for PGDB_C005848
Emax-=27.76%10 uM24 hBRAF-A375.10AU2022290851A1PGDB_A014825PGDB_C005848PGDB_AS000362View
2D structure for PGDB_C005801
Emax-=11.48%10 uM24 hBRAF-A375.10AU2022290851A1PGDB_A015416PGDB_C005801PGDB_AS000362View
2D structure for PGDB_C005846
Emax-=26.33%10 uM24 hBRAF-A375.10AU2022290851A1PGDB_A015813PGDB_C005846PGDB_AS000362View
2D structure for PGDB_C005853
Emax-=23.85%10 uM24 hBRAF-A375.10AU2022290851A1PGDB_A015851PGDB_C005853PGDB_AS000362View
2D structure for PGDB_C005847
Emax-=89.38%10 uM24 hBRAF-A375.10AU2022290851A1PGDB_A016029PGDB_C005847PGDB_AS000362View
2D structure for PGDB_C005811
Emax-=23.85%10 uM24 hBRAF-A375.10AU2022290851A1PGDB_A017966PGDB_C005811PGDB_AS000362View
2D structure for PGDB_C005810
Emax-=18.8%10 uM24 hBRAF-A375.10AU2022290851A1PGDB_A018918PGDB_C005810PGDB_AS000362View
2D structure for PGDB_C005838
Emax-=24.05%10 uM24 hBRAF-A375.10AU2022290851A1PGDB_A020942PGDB_C005838PGDB_AS000362View
2D structure for PGDB_C005808
Emax-=20.97%10 uM24 hBRAF-A375.10AU2022290851A1PGDB_A021722PGDB_C005808PGDB_AS000362View
2D structure for PGDB_C005819
Emax-=14.13%10 uM24 hBRAF-A375.10AU2022290851A1PGDB_A025999PGDB_C005819PGDB_AS000362View
2D structure for PGDB_C005797
Emax-=14.99%10 uM24 hBRAF-A375.10AU2022290851A1PGDB_A027234PGDB_C005797PGDB_AS000362View
2D structure for PGDB_C005652
Emax-=27.48%10 uM24 hBRAF-A375.10AU2022290851A1PGDB_A029003PGDB_C005652PGDB_AS000362View
2D structure for PGDB_C005837
Emax-=25.06%10 uM24 hBRAF-A375.10AU2022290851A1PGDB_A029132PGDB_C005837PGDB_AS000362View
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