Assay

PGDB_AS001308

System: cell_basedTarget: BRAFCell line: A375.10
Assay context summary

Assay context

61 activity records
Assay family% Degradation
Systemcell_based
ReadoutDC50
TargetBRAF
E3Not specified
Cell lineA375.10
Technologyluminescence
Activity compounds and values

Activity records

61 records
StructureMetricControlRelationValueUnitConcentrationTimeTargetE3Cell linePatentRecord IDCompoundAssayDetails
2D structure for PGDB_C005855
DC50-=29.77nM-—BRAF-A375.10AU2022290851A1PGDB_A007202PGDB_C005855PGDB_AS001308View
2D structure for PGDB_C005839
DC50-=40.61nM-—BRAF-A375.10AU2022290851A1PGDB_A007370PGDB_C005839PGDB_AS001308View
2D structure for PGDB_C005806
DC50-=24.61nM-—BRAF-A375.10AU2022290851A1PGDB_A008375PGDB_C005806PGDB_AS001308View
2D structure for PGDB_C005798
DC50-=22.19nM-—BRAF-A375.10AU2022290851A1PGDB_A009098PGDB_C005798PGDB_AS001308View
2D structure for PGDB_C005851
DC50-=15.94nM-—BRAF-A375.10AU2022290851A1PGDB_A012485PGDB_C005851PGDB_AS001308View
2D structure for PGDB_C005807
DC50-=23.22nM-—BRAF-A375.10AU2022290851A1PGDB_A013377PGDB_C005807PGDB_AS001308View
2D structure for PGDB_C005850
DC50-=21.72nM-—BRAF-A375.10AU2022290851A1PGDB_A013683PGDB_C005850PGDB_AS001308View
2D structure for PGDB_C005833
DC50-=16.21nM-—BRAF-A375.10AU2022290851A1PGDB_A016552PGDB_C005833PGDB_AS001308View
2D structure for PGDB_C005810
DC50-=6.98nM-—BRAF-A375.10AU2022290851A1PGDB_A017615PGDB_C005810PGDB_AS001308View
2D structure for PGDB_C005812
DC50-=41.57nM-—BRAF-A375.10AU2022290851A1PGDB_A018277PGDB_C005812PGDB_AS001308View
2D structure for PGDB_C005837
DC50-=16.31nM-—BRAF-A375.10AU2022290851A1PGDB_A019467PGDB_C005837PGDB_AS001308View
2D structure for PGDB_C005828
DC50-=18.04nM-—BRAF-A375.10AU2022290851A1PGDB_A020509PGDB_C005828PGDB_AS001308View
2D structure for PGDB_C005834
DC50-=28.56nM-—BRAF-A375.10AU2022290851A1PGDB_A021088PGDB_C005834PGDB_AS001308View
2D structure for PGDB_C005853
DC50-=5.17nM-—BRAF-A375.10AU2022290851A1PGDB_A024162PGDB_C005853PGDB_AS001308View
2D structure for PGDB_C005802
DC50-=12.37nM-—BRAF-A375.10AU2022290851A1PGDB_A027737PGDB_C005802PGDB_AS001308View
2D structure for PGDB_C005830
DC50-=27.81nM-—BRAF-A375.10AU2022290851A1PGDB_A027894PGDB_C005830PGDB_AS001308View
2D structure for PGDB_C005803
DC50-=18.67nM-—BRAF-A375.10AU2022290851A1PGDB_A028617PGDB_C005803PGDB_AS001308View
2D structure for PGDB_C005829
DC50-=6.13nM-—BRAF-A375.10AU2022290851A1PGDB_A029025PGDB_C005829PGDB_AS001308View
2D structure for PGDB_C005825
DC50-=25.55nM-—BRAF-A375.10AU2022290851A1PGDB_A029600PGDB_C005825PGDB_AS001308View
2D structure for PGDB_C005799
DC50-=26.91nM-—BRAF-A375.10AU2022290851A1PGDB_A029605PGDB_C005799PGDB_AS001308View
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