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Compound
PGDB_C010701
8 activity records1 related patents
2D structure
C=CC(=O)N1CC2(CCCC2c2[nH]c3nnc(-c4cc(F)cc(F)c4O)cc3c2C)C1Compound summary
Physicochemical properties
Activity compounds and values
Activity records
| Structure | Control | Value | Concentration | Time | Record ID | Compound | Assay | Details | |||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| DC50 | - | < | 0.5 | uM | - | — | SMARCA2 | - | HeLa | WO2025101944 | PGDB_A007800 | PGDB_C010701 | PGDB_AS000900 | View |
| % Degradation | - | > | 70 | % | 1 uM | 24 h | SMARCA4 | - | HeLa | WO2025101944 | PGDB_A008201 | PGDB_C010701 | PGDB_AS002120 | View |
| DC50 | - | < | 0.5 | uM | - | — | SMARCA2 | - | HeLa | WO2025101944 | PGDB_A011860 | PGDB_C010701 | PGDB_AS000900 | View |
| % Degradation | - | = | 30-70 | % | 1 uM | 24 h | SMARCA2 | - | HeLa | WO2025101944 | PGDB_A032499 | PGDB_C010701 | PGDB_AS001961 | View |
| % Degradation | - | > | 70 | % | 1 uM | 24 h | SMARCA2 | - | HeLa | WO2025101944 | PGDB_A040723 | PGDB_C010701 | PGDB_AS001961 | View |
| DC50 | - | < | 0.5 | uM | - | — | SMARCA4 | - | HeLa | WO2025101944 | PGDB_A043141 | PGDB_C010701 | PGDB_AS000431 | View |
| % Degradation | - | < | 30 | % | 1 uM | 24 h | SMARCA4 | - | HeLa | WO2025101944 | PGDB_A049672 | PGDB_C010701 | PGDB_AS002120 | View |
| DC50 | - | > | 5 | uM | - | — | SMARCA4 | - | HeLa | WO2025101944 | PGDB_A073481 | PGDB_C010701 | PGDB_AS000431 | View |