PatGlueDB | Molecular Glue Patent Bioactivity Database

Assay context summary

Assay context

644 activity records

Assay family% Degradation

Systemcell_based

Readout% Degradation

TargetSMARCA2

E3Not specified

Cell lineHeLa

OrganismHomo sapiens

Technologyluminescence

Activity compounds and values

Activity records

644 records

Metric	Control	Relation	Value	Unit	Concentration	Time	Target	E3	Cell line	Patent	Record ID	Compound	Assay	Details
% Degradation	-	>	70	%	1 uM	24 h	SMARCA2	-	HeLa	WO2025101944	PGDB_A007016	PGDB_C010524	PGDB_AS001961	View
% Degradation	-	>	70	%	1 uM	24 h	SMARCA2	-	HeLa	WO2025101944	PGDB_A007198	PGDB_C010647	PGDB_AS001961	View
% Degradation	-	=	30-70	%	1 uM	24 h	SMARCA2	-	HeLa	WO2025101944	PGDB_A007365	PGDB_C010703	PGDB_AS001961	View
% Degradation	-	<	30	%	1 uM	24 h	SMARCA2	-	HeLa	WO2025101944	PGDB_A007596	PGDB_C010266	PGDB_AS001961	View
% Degradation	-	>	70	%	1 uM	24 h	SMARCA2	-	HeLa	WO2025101944	PGDB_A007666	PGDB_C010478	PGDB_AS001961	View
% Degradation	-	=	30-70	%	1 uM	24 h	SMARCA2	-	HeLa	WO2025101944	PGDB_A007855	PGDB_C010298	PGDB_AS001961	View
% Degradation	-	=	30-70	%	1 uM	24 h	SMARCA2	-	HeLa	WO2025101944	PGDB_A008128	PGDB_C010594	PGDB_AS001961	View
% Degradation	-	=	30-70	%	1 uM	24 h	SMARCA2	-	HeLa	WO2025101944	PGDB_A008383	PGDB_C010333	PGDB_AS001961	View
% Degradation	-	=	30-70	%	1 uM	24 h	SMARCA2	-	HeLa	WO2025101944	PGDB_A008476	PGDB_C010389	PGDB_AS001961	View
% Degradation	-	<	30	%	1 uM	24 h	SMARCA2	-	HeLa	WO2025101944	PGDB_A008490	PGDB_C010383	PGDB_AS001961	View
% Degradation	-	>	70	%	1 uM	24 h	SMARCA2	-	HeLa	WO2025101944	PGDB_A008569	PGDB_C010789	PGDB_AS001961	View
% Degradation	-	>	70	%	1 uM	24 h	SMARCA2	-	HeLa	WO2025101944	PGDB_A008642	PGDB_C010373	PGDB_AS001961	View
% Degradation	-	>	70	%	1 uM	24 h	SMARCA2	-	HeLa	WO2025101944	PGDB_A008677	PGDB_C010653	PGDB_AS001961	View
% Degradation	-	=	30-70	%	1 uM	24 h	SMARCA2	-	HeLa	WO2025101944	PGDB_A009054	PGDB_C010705	PGDB_AS001961	View
% Degradation	-	<	30	%	1 uM	24 h	SMARCA2	-	HeLa	WO2025101944	PGDB_A009060	PGDB_C010360	PGDB_AS001961	View
% Degradation	-	=	30-70	%	1 uM	24 h	SMARCA2	-	HeLa	WO2025101944	PGDB_A009212	PGDB_C010534	PGDB_AS001961	View
% Degradation	-	=	30-70	%	1 uM	24 h	SMARCA2	-	HeLa	WO2025101944	PGDB_A009271	PGDB_C010755	PGDB_AS001961	View
% Degradation	-	>	70	%	1 uM	24 h	SMARCA2	-	HeLa	WO2025101944	PGDB_A009332	PGDB_C010820	PGDB_AS001961	View
% Degradation	-	=	30-70	%	1 uM	24 h	SMARCA2	-	HeLa	WO2025101944	PGDB_A009489	PGDB_C010779	PGDB_AS001961	View
% Degradation	-	=	30-70	%	1 uM	24 h	SMARCA2	-	HeLa	WO2025101944	PGDB_A009601	PGDB_C010496	PGDB_AS001961	View

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