Loading compound
Loading detail record from the SQLite release...
Compound
PGDB_C012086
4 activity records1 related patents
2D structure
Cc1cnc(N2CCC(CN3CCN(Cc4ccn5nc(F)c(N6CCC(=O)NC6=O)c5c4)C[C@@H]3C)CC2)nc1Compound summary
Physicochemical properties
Activity compounds and values
Activity records
| Structure | Control | Value | Concentration | Time | Record ID | Compound | Assay | Details | |||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| EC50 | - | < | 10 | nM | - | — | - | - | primary human CD34+ cells | WO2025256460A1 | PGDB_A034031 | PGDB_C012086 | PGDB_AS000793 | View |
| Dmax | - | = | 93.8 | % | Concentration series: 10 uM, 0.316 nM | 20 h | WIZ | - | HT-1080 | WO2025256460A1 | PGDB_A034659 | PGDB_C012086 | PGDB_AS002062 | View |
| DC50 | - | = | 15.6 | nM | - | — | WIZ | - | HT-1080 | WO2025256460A1 | PGDB_A049781 | PGDB_C012086 | PGDB_AS000508 | View |
| Emax | - | = | 84.2 | % | - | 7 d | - | - | primary human CD34+ cells | WO2025256460A1 | PGDB_A060423 | PGDB_C012086 | PGDB_AS001133 | View |