Loading compound
Loading detail record from the SQLite release...
Compound
PGDB_C012087
4 activity records1 related patents
2D structure
C[C@H]1CN(Cc2ccn3nc(F)c(N4CCC(=O)NC4=O)c3c2)CCN1CC1CCN(c2ncccn2)CC1Compound summary
Physicochemical properties
Activity compounds and values
Activity records
| Structure | Control | Value | Concentration | Time | Record ID | Compound | Assay | Details | |||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Dmax | - | = | 91.6 | % | Concentration series: 10 uM, 0.316 nM | 20 h | WIZ | - | HT-1080 | WO2025256460A1 | PGDB_A036384 | PGDB_C012087 | PGDB_AS002062 | View |
| EC50 | - | < | 10 | nM | - | — | - | - | primary human CD34+ cells | WO2025256460A1 | PGDB_A050916 | PGDB_C012087 | PGDB_AS000793 | View |
| DC50 | - | = | 20.1 | nM | - | — | WIZ | - | HT-1080 | WO2025256460A1 | PGDB_A071746 | PGDB_C012087 | PGDB_AS000508 | View |
| Emax | - | = | 87.8 | % | - | 7 d | - | - | primary human CD34+ cells | WO2025256460A1 | PGDB_A077164 | PGDB_C012087 | PGDB_AS001133 | View |