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Compound
PGDB_C012088
4 activity records1 related patents
2D structure
C[C@H]1CN(Cc2ccn3nc(F)c(N4CCC(=O)NC4=O)c3c2)CCN1CC1CCN(c2ccc(Cl)cn2)CC1Compound summary
Physicochemical properties
Activity compounds and values
Activity records
| Structure | Control | Value | Concentration | Time | Record ID | Compound | Assay | Details | |||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Dmax | - | = | 95 | % | Concentration series: 10 uM, 0.316 nM | 20 h | WIZ | - | HT-1080 | WO2025256460A1 | PGDB_A013339 | PGDB_C012088 | PGDB_AS002062 | View |
| EC50 | - | < | 10 | nM | - | — | - | - | primary human CD34+ cells | WO2025256460A1 | PGDB_A037389 | PGDB_C012088 | PGDB_AS000793 | View |
| DC50 | - | = | 13.7 | nM | - | — | WIZ | - | HT-1080 | WO2025256460A1 | PGDB_A065427 | PGDB_C012088 | PGDB_AS000508 | View |
| Emax | - | = | 77.2 | % | - | 7 d | - | - | primary human CD34+ cells | WO2025256460A1 | PGDB_A066916 | PGDB_C012088 | PGDB_AS001133 | View |