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C[C@H]1CN(Cc2ccn3nc(F)c(N4CCC(=O)NC4=O)c3c2)CCN1C[C@@H]1[C@@H]2C[C@H]1CN(c1ncccn1)C2| Structure | Control | Value | Concentration | Time | Record ID | Compound | Assay | Details | |||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| DC50 | - | = | 11.9 | nM | - | — | WIZ | - | HT-1080 | WO2025256460A1 | PGDB_A008330 | PGDB_C012106 | PGDB_AS000508 | View | |
| Dmax | - | = | 92.7 | % | Concentration series: 10 uM, 0.316 nM | 20 h | WIZ | - | HT-1080 | WO2025256460A1 | PGDB_A076681 | PGDB_C012106 | PGDB_AS002062 | View |