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Cc1cn(C)nc1C1CCC(CN2CCN(Cc3ccn4nc(F)c(N5CCC(=O)NC5=O)c4c3)C[C@@H]2C)CC1| Structure | Control | Value | Concentration | Time | Record ID | Compound | Assay | Details | |||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| DC50 | - | = | 11 | nM | - | — | WIZ | - | HT-1080 | WO2025256460A1 | PGDB_A015395 | PGDB_C012135 | PGDB_AS000508 | View | |
| Dmax | - | = | 94.6 | % | Concentration series: 10 uM, 0.316 nM | 20 h | WIZ | - | HT-1080 | WO2025256460A1 | PGDB_A046116 | PGDB_C012135 | PGDB_AS002062 | View |