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Compound
PGDB_C015373
5 activity records2 related patents
2D structure
CC1(n2cc(Cc3ccc4c5c(cccc35)C(=O)N4C3CCC(=O)NC3=O)cn2)CCN(C(=O)C2(C(F)(F)F)CC2)CC1Compound summary
Physicochemical properties
Activity compounds and values
Activity records
| Structure | Control | Value | Concentration | Time | Record ID | Compound | Assay | Details | |||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| DC50 | - | < | 100 | nM | - | — | - | - | KELLY.2 | WO2022081927A1 | PGDB_A015421 | PGDB_C015373 | PGDB_AS001296 | View |
| IC50 | - | < | 1 | nM | - | — | - | - | NCI-H929 | EA048567B1 | PGDB_A038393 | PGDB_C015373 | PGDB_AS000412 | View |
| Emax | - | < | 45 | % | - | DC50 > 10000 nM | DC50 >= 100 nM and <= 1000 nM | > 100 nM | - | - | KELLY.2 | WO2022081927A1 | PGDB_A038760 | PGDB_C015373 | PGDB_AS000499 | View |
| Emax | - | > | 60 | % | - | DC50 > 10000 nM | > 100 nM | DC50 < 100 nM | - | - | 293T.114 | WO2022081927A1 | PGDB_A047412 | PGDB_C015373 | PGDB_AS000287 | View |
| DC50 | - | > | 10000 | nM | - | — | - | - | 293T.114 | WO2022081927A1 | PGDB_A065502 | PGDB_C015373 | PGDB_AS001223 | View |