Loading compound
Loading detail record from the SQLite release...
Compound
PGDB_C019485
7 activity records1 related patents
2D structure
O=C1CCC(N2C(=O)c3ccc(CN4CCN(c5ncncn5)CC4)cc3C2=O)C(=O)N1Compound summary
Physicochemical properties
Activity compounds and values
Activity records
| Structure | Control | Value | Concentration | Time | Record ID | Compound | Assay | Details | |||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| % Degradation | - | >= | 20 | % | Concentration series: 500 nM, 50 nM | 24 h | GSPT1 | - | - | WO2025016359A1 | PGDB_A010655 | PGDB_C019485 | PGDB_AS000700 | View |
| % Degradation | - | >= | 0 | % | Concentration series: 500 nM, 50 nM | 24 h | IKZF3 | - | - | WO2025016359A1 | PGDB_A017099 | PGDB_C019485 | PGDB_AS002465 | View |
| % Degradation | - | >= | 0 | % | Concentration series: 500 nM, 50 nM | 24 h | IKZF1 | - | - | WO2025016359A1 | PGDB_A018909 | PGDB_C019485 | PGDB_AS001760 | View |
| % Degradation | - | >= | 0 | % | Concentration series: 500 nM, 50 nM | 24 h | CSNK1A1 | - | - | WO2025016359A1 | PGDB_A047600 | PGDB_C019485 | PGDB_AS001647 | View |
| % Degradation | - | >= | 0 | % | Concentration series: 500 nM, 50 nM | 24 h | IKZF2 | - | - | WO2025016359A1 | PGDB_A054319 | PGDB_C019485 | PGDB_AS002547 | View |
| IC50 | - | = | 50-100 | nM | - | — | - | - | MV-4-11 | WO2025016359A1 | PGDB_A054709 | PGDB_C019485 | PGDB_AS001504 | View |
| % Degradation | - | >= | 0 | % | Concentration series: 500 nM, 50 nM | 24 h | WEE1 | - | - | WO2025016359A1 | PGDB_A065248 | PGDB_C019485 | PGDB_AS000593 | View |