PatGlueDB | Molecular Glue Patent Bioactivity Database

Assay context summary

Assay context

357 activity records

Assay family% Degradation

Systemcell_based

Readoutpercent_remaining

E3Not specified

OrganismHomo sapiens

TechnologyWestern_blot

Detection targetprotein_degradation

Activity compounds and values

Activity records

357 records

Metric	Control	Relation	Value	Unit	Concentration	Time	Target	E3	Cell line	Patent	Record ID	Compound	Assay	Details
% Degradation	-	>=	20	%	Concentration series: 500 nM, 50 nM	24 h	GSPT1	-	-	WO2025016359A1	PGDB_A007162	PGDB_C019503	PGDB_AS000700	View
% Degradation	-	>=	20	%	Concentration series: 500 nM, 50 nM	24 h	GSPT1	-	-	WO2025016359A1	PGDB_A007210	PGDB_C019229	PGDB_AS000700	View
% Degradation	-	>=	20	%	Concentration series: 500 nM, 50 nM	24 h	GSPT1	-	-	WO2025016359A1	PGDB_A007343	PGDB_C019358	PGDB_AS000700	View
% Degradation	-	>=	20	%	Concentration series: 500 nM, 50 nM	24 h	GSPT1	-	-	WO2025016359A1	PGDB_A007679	PGDB_C019312	PGDB_AS000700	View
% Degradation	-	>=	20	%	Concentration series: 500 nM, 50 nM	24 h	GSPT1	-	-	WO2025016359A1	PGDB_A007702	PGDB_C019197	PGDB_AS000700	View
% Degradation	-	>=	20	%	Concentration series: 500 nM, 50 nM	24 h	GSPT1	-	-	WO2025016359A1	PGDB_A007772	PGDB_C019303	PGDB_AS000700	View
% Degradation	-	>=	20	%	Concentration series: 500 nM, 50 nM	24 h	GSPT1	-	-	WO2025016359A1	PGDB_A007842	PGDB_C019255	PGDB_AS000700	View
% Degradation	-	>=	20	%	Concentration series: 500 nM, 50 nM	24 h	GSPT1	-	-	WO2025016359A1	PGDB_A008059	PGDB_C019473	PGDB_AS000700	View
% Degradation	-	>=	0	%	Concentration series: 500 nM, 50 nM	24 h	GSPT1	-	-	WO2025016359A1	PGDB_A008071	PGDB_C019526	PGDB_AS000700	View
% Degradation	-	>=	20	%	Concentration series: 500 nM, 50 nM	24 h	GSPT1	-	-	WO2025016359A1	PGDB_A008310	PGDB_C019402	PGDB_AS000700	View
% Degradation	-	>=	20	%	Concentration series: 500 nM, 50 nM	24 h	GSPT1	-	-	WO2025016359A1	PGDB_A008611	PGDB_C019459	PGDB_AS000700	View
% Degradation	-	>=	20	%	Concentration series: 500 nM, 50 nM	24 h	GSPT1	-	-	WO2025016359A1	PGDB_A008826	PGDB_C019329	PGDB_AS000700	View
% Degradation	-	>=	20	%	Concentration series: 500 nM, 50 nM	24 h	GSPT1	-	-	WO2025016359A1	PGDB_A009719	PGDB_C019505	PGDB_AS000700	View
% Degradation	-	>=	20	%	Concentration series: 500 nM, 50 nM	24 h	GSPT1	-	-	WO2025016359A1	PGDB_A009924	PGDB_C019327	PGDB_AS000700	View
% Degradation	-	>=	0	%	Concentration series: 500 nM, 50 nM	24 h	GSPT1	-	-	WO2025016359A1	PGDB_A009956	PGDB_C019357	PGDB_AS000700	View
% Degradation	-	>=	20	%	Concentration series: 500 nM, 50 nM	24 h	GSPT1	-	-	WO2025016359A1	PGDB_A010035	PGDB_C019435	PGDB_AS000700	View
% Degradation	-	>=	20	%	Concentration series: 500 nM, 50 nM	24 h	GSPT1	-	-	WO2025016359A1	PGDB_A010103	PGDB_C019500	PGDB_AS000700	View
% Degradation	-	>=	20	%	Concentration series: 500 nM, 50 nM	24 h	GSPT1	-	-	WO2025016359A1	PGDB_A010120	PGDB_C019513	PGDB_AS000700	View
% Degradation	-	>=	20	%	Concentration series: 500 nM, 50 nM	24 h	GSPT1	-	-	WO2025016359A1	PGDB_A010376	PGDB_C019451	PGDB_AS000700	View
% Degradation	-	>=	20	%	Concentration series: 500 nM, 50 nM	24 h	GSPT1	-	-	WO2025016359A1	PGDB_A010487	PGDB_C019422	PGDB_AS000700	View

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