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Compound
PGDB_C020381
4 activity records2 related patents
2D structure
CC(C)(C(=O)NCc1cc(Cl)c(C2CCC(=O)NC2=O)c(Cl)c1)c1nnc(C(F)(F)F)o1Compound summary
Physicochemical properties
Activity compounds and values
Activity records
| Structure | Control | Value | Concentration | Time | Record ID | Compound | Assay | Details | |||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| DC50 | - | = | 345 | nM | - | — | NEK7 | - | CAL-51 | WO2025024521A1 | PGDB_A007549 | PGDB_C020381 | PGDB_AS001365 | View |
| Dmax | - | > | 50 | % | Concentration context: various concentrations | 24 h | - | - | CAL-51 | KR20260041885A | PGDB_A014304 | PGDB_C020381 | PGDB_AS000078 | View |
| Dmax | - | = | 56 | % | Concentration series: 1 uM, 0.05 nM | 24 h | NEK7 | - | CAL-51 | WO2025024521A1 | PGDB_A061184 | PGDB_C020381 | PGDB_AS002061 | View |
| EC50 | - | = | 0.17 | uM | - | — | CRBN | CRBN | - | WO2025024521A1 | PGDB_A069954 | PGDB_C020381 | PGDB_AS001033 | View |