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Compound
PGDB_C022076
8 activity records1 related patents
2D structure
O=C1CCC(N2Cc3c(CN4C5CCC4CN(C(c4ccccc4)c4ccccc4)C5)cccc3C2=S)C(=O)N1Compound summary
Physicochemical properties
Activity compounds and values
Activity records
| Structure | Control | Value | Concentration | Time | Record ID | Compound | Assay | Details | |||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| % Degradation | - | = | 0-80 | % | - | - | GSPT1 | - | - | CN119654316A | PGDB_A081919 | PGDB_C022076 | PGDB_AS000660 | View |
| % Degradation | - | = | 80-100 | % | - | - | IKZF3 | - | - | CN119654316A | PGDB_A083038 | PGDB_C022076 | PGDB_AS000017 | View |
| % Inhibition | - | = | 30-40 | % | 0.5 uM | 3 h | CRBN | CRBN | - | CN119654316A | PGDB_A083199 | PGDB_C022076 | PGDB_AS001405 | View |
| % Degradation | - | = | 80-100 | % | - | - | - | - | - | CN119654316A | PGDB_A083567 | PGDB_C022076 | PGDB_AS000466 | View |
| % Inhibition | - | = | 60-80 | % | 2 uM | 3 h | CRBN | CRBN | - | CN119654316A | PGDB_A084182 | PGDB_C022076 | PGDB_AS002552 | View |
| % Degradation | - | = | 80-100 | % | - | - | IKZF1 | - | - | CN119654316A | PGDB_A084704 | PGDB_C022076 | PGDB_AS001680 | View |
| % Degradation | - | = | 80-100 | % | - | - | WEE1 | - | - | CN119654316A | PGDB_A085232 | PGDB_C022076 | PGDB_AS001023 | View |
| % Degradation | - | = | 80-100 | % | - | - | IKZF2 | - | - | CN119654316A | PGDB_A085246 | PGDB_C022076 | PGDB_AS002430 | View |