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Compound
PGDB_C022104
10 activity records1 related patents
2D structure
S=C1NCc2cc(CN3CC4CC(C3)N4c3cccc(Cl)c3Cl)ccc21Compound summary
Physicochemical properties
Activity compounds and values
Activity records
| Structure | Control | Value | Concentration | Time | Record ID | Compound | Assay | Details | |||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| % Inhibition | - | = | 53-60 | % | 0.5 uM | 3 h | CRBN | CRBN | - | CN119654316A | PGDB_A082025 | PGDB_C022104 | PGDB_AS001405 | View |
| % Degradation | - | = | 80-100 | % | - | - | IKZF1 | - | - | CN119654316A | PGDB_A082440 | PGDB_C022104 | PGDB_AS001680 | View |
| % Inhibition | - | = | 60-80 | % | 2 uM | 3 h | CRBN | CRBN | - | CN119654316A | PGDB_A082751 | PGDB_C022104 | PGDB_AS002552 | View |
| % Inhibition | - | = | 40-50 | % | 500 nM | - | - | - | MM.1S | CN119654316A | PGDB_A082769 | PGDB_C022104 | PGDB_AS000639 | View |
| % Inhibition | - | = | 5-10 | % | 10 nM | - | - | - | MM.1S | CN119654316A | PGDB_A083009 | PGDB_C022104 | PGDB_AS000042 | View |
| % Degradation | - | = | 0-80 | % | - | - | IKZF3 | - | - | CN119654316A | PGDB_A083216 | PGDB_C022104 | PGDB_AS000017 | View |
| % Degradation | - | = | 80-100 | % | - | - | - | - | - | CN119654316A | PGDB_A083503 | PGDB_C022104 | PGDB_AS000466 | View |
| % Degradation | - | = | 80-100 | % | - | - | IKZF2 | - | - | CN119654316A | PGDB_A084599 | PGDB_C022104 | PGDB_AS002430 | View |
| % Degradation | - | = | 80-100 | % | - | - | GSPT1 | - | - | CN119654316A | PGDB_A085337 | PGDB_C022104 | PGDB_AS000660 | View |
| % Degradation | - | = | 80-100 | % | - | - | WEE1 | - | - | CN119654316A | PGDB_A085529 | PGDB_C022104 | PGDB_AS001023 | View |