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Compound
PGDB_C022139
8 activity records1 related patents
2D structure
Cc1ccccc1N1CCN(Cc2ccc3c(c2)CN([C@@H]2CCC(=O)NC2=O)C3=S)CC1Compound summary
Physicochemical properties
Activity compounds and values
Activity records
| Structure | Control | Value | Concentration | Time | Record ID | Compound | Assay | Details | |||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| % Inhibition | - | = | 60-80 | % | 2 uM | 3 h | CRBN | CRBN | - | CN119654316A | PGDB_A081916 | PGDB_C022139 | PGDB_AS002552 | View |
| % Degradation | - | = | 80-100 | % | - | - | IKZF1 | - | - | CN119654316A | PGDB_A082734 | PGDB_C022139 | PGDB_AS001680 | View |
| % Degradation | - | = | 80-100 | % | - | - | WEE1 | - | - | CN119654316A | PGDB_A084694 | PGDB_C022139 | PGDB_AS001023 | View |
| % Inhibition | - | = | 30-40 | % | 0.5 uM | 3 h | CRBN | CRBN | - | CN119654316A | PGDB_A084809 | PGDB_C022139 | PGDB_AS001405 | View |
| % Degradation | - | = | 80-100 | % | - | - | IKZF3 | - | - | CN119654316A | PGDB_A085082 | PGDB_C022139 | PGDB_AS000017 | View |
| % Degradation | - | = | 80-100 | % | - | - | IKZF2 | - | - | CN119654316A | PGDB_A085194 | PGDB_C022139 | PGDB_AS002430 | View |
| % Degradation | - | = | 0-80 | % | - | - | GSPT1 | - | - | CN119654316A | PGDB_A085248 | PGDB_C022139 | PGDB_AS000660 | View |
| % Degradation | - | = | 80-100 | % | - | - | - | - | - | CN119654316A | PGDB_A085647 | PGDB_C022139 | PGDB_AS000466 | View |