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Compound
PGDB_C022267
10 activity records1 related patents
2D structure
O=C1CCC(N2Cc3c(CN4CCC(c5ncnc6sc7c(c56)CCC7)CC4)cccc3C2=S)C(=O)N1Compound summary
Physicochemical properties
Activity compounds and values
Activity records
| Structure | Control | Value | Concentration | Time | Record ID | Compound | Assay | Details | |||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| % Degradation | - | = | 80-100 | % | - | - | - | - | - | CN119654316A | PGDB_A082038 | PGDB_C022267 | PGDB_AS000466 | View |
| % Inhibition | - | = | 30-40 | % | 10 nM | - | - | - | MCF-7 | CN119654316A | PGDB_A082799 | PGDB_C022267 | PGDB_AS002350 | View |
| % Inhibition | - | = | 40-50 | % | 500 nM | - | - | - | MCF-7 | CN119654316A | PGDB_A083658 | PGDB_C022267 | PGDB_AS001118 | View |
| % Inhibition | - | = | 30-40 | % | 0.5 uM | 3 h | CRBN | CRBN | - | CN119654316A | PGDB_A084762 | PGDB_C022267 | PGDB_AS001405 | View |
| % Inhibition | - | = | 40-53 | % | 2 uM | 3 h | CRBN | CRBN | - | CN119654316A | PGDB_A085057 | PGDB_C022267 | PGDB_AS002552 | View |
| % Degradation | - | = | 0-80 | % | - | - | GSPT1 | - | - | CN119654316A | PGDB_A085088 | PGDB_C022267 | PGDB_AS000660 | View |
| % Degradation | - | = | 0-80 | % | - | - | IKZF1 | - | - | CN119654316A | PGDB_A085095 | PGDB_C022267 | PGDB_AS001680 | View |
| % Degradation | - | = | 0-80 | % | - | - | WEE1 | - | - | CN119654316A | PGDB_A085347 | PGDB_C022267 | PGDB_AS001023 | View |
| % Degradation | - | = | 80-100 | % | - | - | IKZF2 | - | - | CN119654316A | PGDB_A085371 | PGDB_C022267 | PGDB_AS002430 | View |
| % Degradation | - | = | 0-80 | % | - | - | IKZF3 | - | - | CN119654316A | PGDB_A085748 | PGDB_C022267 | PGDB_AS000017 | View |