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Compound
PGDB_C022272
10 activity records1 related patents
2D structure
Cc1cc2c(C3=CCN(Cc4cccc5c4CN(C4CCC(=O)NC4=O)C5=S)CC3)ncnc2s1Compound summary
Physicochemical properties
Activity compounds and values
Activity records
| Structure | Control | Value | Concentration | Time | Record ID | Compound | Assay | Details | |||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| % Inhibition | - | = | 60-80 | % | 2 uM | 3 h | CRBN | CRBN | - | CN119654316A | PGDB_A082081 | PGDB_C022272 | PGDB_AS002552 | View |
| % Degradation | - | = | 80-100 | % | - | - | IKZF3 | - | - | CN119654316A | PGDB_A082187 | PGDB_C022272 | PGDB_AS000017 | View |
| % Inhibition | - | = | 40-50 | % | 500 nM | - | - | - | MM.1S | CN119654316A | PGDB_A082346 | PGDB_C022272 | PGDB_AS000639 | View |
| % Degradation | - | = | 80-100 | % | - | - | IKZF1 | - | - | CN119654316A | PGDB_A082733 | PGDB_C022272 | PGDB_AS001680 | View |
| % Degradation | - | = | 80-100 | % | - | - | GSPT1 | - | - | CN119654316A | PGDB_A083140 | PGDB_C022272 | PGDB_AS000660 | View |
| % Inhibition | - | = | 30-40 | % | 10 nM | - | - | - | MM.1S | CN119654316A | PGDB_A083149 | PGDB_C022272 | PGDB_AS000042 | View |
| % Inhibition | - | = | 53-60 | % | 0.5 uM | 3 h | CRBN | CRBN | - | CN119654316A | PGDB_A083804 | PGDB_C022272 | PGDB_AS001405 | View |
| % Degradation | - | = | 80-100 | % | - | - | IKZF2 | - | - | CN119654316A | PGDB_A083887 | PGDB_C022272 | PGDB_AS002430 | View |
| % Degradation | - | = | 80-100 | % | - | - | - | - | - | CN119654316A | PGDB_A084054 | PGDB_C022272 | PGDB_AS000466 | View |
| % Degradation | - | = | 0-80 | % | - | - | WEE1 | - | - | CN119654316A | PGDB_A084405 | PGDB_C022272 | PGDB_AS001023 | View |