Loading compound
Loading detail record from the SQLite release...
Compound
PGDB_C022288
10 activity records1 related patents
2D structure
O=C1CC[C@@H](N2Cc3cc(CN4CCN(c5ccnc(Cl)c5Br)CC4)ccc3C2=S)C(=O)N1Compound summary
Physicochemical properties
Activity compounds and values
Activity records
| Structure | Control | Value | Concentration | Time | Record ID | Compound | Assay | Details | |||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| % Inhibition | - | = | 50-60 | % | 10 nM | 96 h | - | - | MOLT-4 | CN119654316A | PGDB_A082043 | PGDB_C022288 | PGDB_AS002038 | View |
| % Inhibition | - | = | 30-40 | % | 500 nM | 96 h | - | - | MOLT-4 | CN119654316A | PGDB_A082198 | PGDB_C022288 | PGDB_AS000121 | View |
| % Degradation | - | = | 0-80 | % | - | - | GSPT1 | - | - | CN119654316A | PGDB_A082851 | PGDB_C022288 | PGDB_AS000660 | View |
| % Inhibition | - | = | 60-80 | % | 2 uM | 3 h | CRBN | CRBN | - | CN119654316A | PGDB_A082869 | PGDB_C022288 | PGDB_AS002552 | View |
| % Degradation | - | = | 80-100 | % | - | - | IKZF3 | - | - | CN119654316A | PGDB_A082874 | PGDB_C022288 | PGDB_AS000017 | View |
| % Degradation | - | = | 80-100 | % | - | - | - | - | - | CN119654316A | PGDB_A083072 | PGDB_C022288 | PGDB_AS000466 | View |
| % Inhibition | - | = | 60-80 | % | 0.5 uM | 3 h | CRBN | CRBN | - | CN119654316A | PGDB_A083258 | PGDB_C022288 | PGDB_AS001405 | View |
| % Degradation | - | = | 0-80 | % | - | - | IKZF1 | - | - | CN119654316A | PGDB_A083592 | PGDB_C022288 | PGDB_AS001680 | View |
| % Degradation | - | = | 80-100 | % | - | - | IKZF2 | - | - | CN119654316A | PGDB_A083710 | PGDB_C022288 | PGDB_AS002430 | View |
| % Degradation | - | = | 80-100 | % | - | - | WEE1 | - | - | CN119654316A | PGDB_A083766 | PGDB_C022288 | PGDB_AS001023 | View |