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Compound
PGDB_C022303
8 activity records1 related patents
2D structure
O=C1CCC(N2Cc3cc(CN4CCC(c5cccc6c(F)cccc56)CC4)ccc3C2=S)C(=O)N1Compound summary
Physicochemical properties
Activity compounds and values
Activity records
| Structure | Control | Value | Concentration | Time | Record ID | Compound | Assay | Details | |||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| % Degradation | - | = | 80-100 | % | - | - | IKZF3 | - | - | CN119654316A | PGDB_A082035 | PGDB_C022303 | PGDB_AS000017 | View |
| % Degradation | - | = | 80-100 | % | - | - | WEE1 | - | - | CN119654316A | PGDB_A082241 | PGDB_C022303 | PGDB_AS001023 | View |
| % Degradation | - | = | 0-80 | % | - | - | GSPT1 | - | - | CN119654316A | PGDB_A082664 | PGDB_C022303 | PGDB_AS000660 | View |
| % Inhibition | - | = | 53-60 | % | 2 uM | 3 h | CRBN | CRBN | - | CN119654316A | PGDB_A082824 | PGDB_C022303 | PGDB_AS002552 | View |
| % Degradation | - | = | 80-100 | % | - | - | IKZF1 | - | - | CN119654316A | PGDB_A083006 | PGDB_C022303 | PGDB_AS001680 | View |
| % Inhibition | - | = | 20-30 | % | 0.5 uM | 3 h | CRBN | CRBN | - | CN119654316A | PGDB_A083788 | PGDB_C022303 | PGDB_AS001405 | View |
| % Degradation | - | = | 80-100 | % | - | - | - | - | - | CN119654316A | PGDB_A084468 | PGDB_C022303 | PGDB_AS000466 | View |
| % Degradation | - | = | 80-100 | % | - | - | IKZF2 | - | - | CN119654316A | PGDB_A085249 | PGDB_C022303 | PGDB_AS002430 | View |