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Compound
PGDB_C022331
10 activity records1 related patents
2D structure
Cc1ccsc1C1CCN(Cc2cccc3c2CN(C2CCC(=O)NC2=O)C3=S)CC1Compound summary
Physicochemical properties
Activity compounds and values
Activity records
| Structure | Control | Value | Concentration | Time | Record ID | Compound | Assay | Details | |||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| % Degradation | - | = | 0-80 | % | - | - | WEE1 | - | - | CN119654316A | PGDB_A081963 | PGDB_C022331 | PGDB_AS001023 | View |
| % Inhibition | - | = | 30-40 | % | 0.5 uM | 3 h | CRBN | CRBN | - | CN119654316A | PGDB_A081976 | PGDB_C022331 | PGDB_AS001405 | View |
| % Inhibition | - | = | 53-60 | % | 2 uM | 3 h | CRBN | CRBN | - | CN119654316A | PGDB_A082004 | PGDB_C022331 | PGDB_AS002552 | View |
| % Degradation | - | = | 80-100 | % | - | - | IKZF1 | - | - | CN119654316A | PGDB_A082350 | PGDB_C022331 | PGDB_AS001680 | View |
| % Inhibition | - | = | 60-80 | % | 500 nM | - | - | - | MV-4-11 | CN119654316A | PGDB_A082612 | PGDB_C022331 | PGDB_AS001323 | View |
| % Degradation | - | = | 80-100 | % | - | - | GSPT1 | - | - | CN119654316A | PGDB_A083942 | PGDB_C022331 | PGDB_AS000660 | View |
| % Inhibition | - | = | 40-60 | % | 10 nM | - | - | - | MV-4-11 | CN119654316A | PGDB_A084279 | PGDB_C022331 | PGDB_AS000053 | View |
| % Degradation | - | = | 80-100 | % | - | - | IKZF2 | - | - | CN119654316A | PGDB_A084616 | PGDB_C022331 | PGDB_AS002430 | View |
| % Degradation | - | = | 80-100 | % | - | - | - | - | - | CN119654316A | PGDB_A085155 | PGDB_C022331 | PGDB_AS000466 | View |
| % Degradation | - | = | 80-100 | % | - | - | IKZF3 | - | - | CN119654316A | PGDB_A085607 | PGDB_C022331 | PGDB_AS000017 | View |