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Compound
PGDB_C022350
8 activity records1 related patents
2D structure
O=C1CCC(N2Cc3cc(CN4CCC(c5ncnc6sc7c(c56)CCC7)CC4)ccc3C2=S)C(=O)N1Compound summary
Physicochemical properties
Activity compounds and values
Activity records
| Structure | Control | Value | Concentration | Time | Record ID | Compound | Assay | Details | |||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| % Degradation | - | = | 0-80 | % | - | - | IKZF1 | - | - | CN119654316A | PGDB_A082105 | PGDB_C022350 | PGDB_AS001680 | View |
| % Inhibition | - | = | 53-60 | % | 0.5 uM | 3 h | CRBN | CRBN | - | CN119654316A | PGDB_A083450 | PGDB_C022350 | PGDB_AS001405 | View |
| % Degradation | - | = | 80-100 | % | - | - | IKZF2 | - | - | CN119654316A | PGDB_A084378 | PGDB_C022350 | PGDB_AS002430 | View |
| % Degradation | - | = | 0-80 | % | - | - | WEE1 | - | - | CN119654316A | PGDB_A084813 | PGDB_C022350 | PGDB_AS001023 | View |
| % Degradation | - | = | 0-80 | % | - | - | IKZF3 | - | - | CN119654316A | PGDB_A085107 | PGDB_C022350 | PGDB_AS000017 | View |
| % Degradation | - | = | 0-80 | % | - | - | GSPT1 | - | - | CN119654316A | PGDB_A085188 | PGDB_C022350 | PGDB_AS000660 | View |
| % Inhibition | - | = | 60-80 | % | 2 uM | 3 h | CRBN | CRBN | - | CN119654316A | PGDB_A085605 | PGDB_C022350 | PGDB_AS002552 | View |
| % Degradation | - | = | 80-100 | % | - | - | - | - | - | CN119654316A | PGDB_A085701 | PGDB_C022350 | PGDB_AS000466 | View |