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Compound
PGDB_C022356
8 activity records1 related patents
2D structure
Cc1nc(C2=CCN(Cc3ccc4c(c3)CN(C3CCC(=O)NC3=O)C4=S)CC2)c2c3c(sc2n1)CCC3Compound summary
Physicochemical properties
Activity compounds and values
Activity records
| Structure | Control | Value | Concentration | Time | Record ID | Compound | Assay | Details | |||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| % Degradation | - | = | 0-80 | % | - | - | GSPT1 | - | - | CN119654316A | PGDB_A082083 | PGDB_C022356 | PGDB_AS000660 | View |
| % Inhibition | - | = | 40-53 | % | 0.5 uM | 3 h | CRBN | CRBN | - | CN119654316A | PGDB_A082398 | PGDB_C022356 | PGDB_AS001405 | View |
| % Degradation | - | = | 80-100 | % | - | - | - | - | - | CN119654316A | PGDB_A082665 | PGDB_C022356 | PGDB_AS000466 | View |
| % Degradation | - | = | 80-100 | % | - | - | IKZF2 | - | - | CN119654316A | PGDB_A083057 | PGDB_C022356 | PGDB_AS002430 | View |
| % Degradation | - | = | 80-100 | % | - | - | IKZF3 | - | - | CN119654316A | PGDB_A083406 | PGDB_C022356 | PGDB_AS000017 | View |
| % Degradation | - | = | 0-80 | % | - | - | WEE1 | - | - | CN119654316A | PGDB_A083726 | PGDB_C022356 | PGDB_AS001023 | View |
| % Degradation | - | = | 80-100 | % | - | - | IKZF1 | - | - | CN119654316A | PGDB_A084578 | PGDB_C022356 | PGDB_AS001680 | View |
| % Inhibition | - | = | 60-80 | % | 2 uM | 3 h | CRBN | CRBN | - | CN119654316A | PGDB_A084962 | PGDB_C022356 | PGDB_AS002552 | View |