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Compound
PGDB_C024489
5 activity records1 related patents
2D structure
COC1(C)CCC(c2ccc(Cl)cc2)=C(CN2CCN(Nc3cc(F)c4c(c3)CN(C3CCC(=O)NC3=O)C4=O)CC2)C1Compound summary
Physicochemical properties
Activity compounds and values
Activity records
| Structure | Control | Value | Concentration | Time | Record ID | Compound | Assay | Details | |||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| % Inhibition | - | = | 20-30 | % | 500 nM | 96 h | IKZF3 | - | MV-4-11 | WO2025162225A1 | PGDB_A008596 | PGDB_C024489 | PGDB_AS001561 | View |
| % Inhibition | - | = | 40-53 | % | 0.5 uM | - | CRBN | CRBN | - | WO2025162225A1 | PGDB_A036821 | PGDB_C024489 | PGDB_AS002133 | View |
| % Inhibition | - | = | 20-30 | % | 0.1 uM | - | IKZF3 | - | - | WO2025162225A1 | PGDB_A042057 | PGDB_C024489 | PGDB_AS002324 | View |
| % Inhibition | - | = | 40-50 | % | 10 nM | 96 h | IKZF3 | - | MV-4-11 | WO2025162225A1 | PGDB_A045042 | PGDB_C024489 | PGDB_AS001155 | View |
| % Inhibition | - | = | 70-80 | % | 2 uM | - | CRBN | CRBN | - | WO2025162225A1 | PGDB_A062344 | PGDB_C024489 | PGDB_AS002540 | View |