Assay

PGDB_AS002133

System: cell_basedTarget: CRBN
Assay context summary

Assay context

239 activity records
Assay familybiochemical
Systemcell_based
Readout% Inhibition
TargetCRBN
E3CRBN
TechnologyHTRF
Detection targetcell_inhibition
Activity compounds and values

Activity records

239 records
StructureMetricControlRelationValueUnitConcentrationTimeTargetE3Cell linePatentRecord IDCompoundAssayDetails
2D structure for PGDB_C024491
% Inhibition-=53-60%0.5 uM-CRBNCRBN-WO2025162225A1PGDB_A007153PGDB_C024491PGDB_AS002133View
2D structure for PGDB_C024433
% Inhibition-=30-40%0.5 uM-CRBNCRBN-WO2025162225A1PGDB_A007819PGDB_C024433PGDB_AS002133View
2D structure for PGDB_C024246
% Inhibition-=40-53%0.5 uM-CRBNCRBN-WO2025162225A1PGDB_A007854PGDB_C024246PGDB_AS002133View
2D structure for PGDB_C024480
% Inhibition-=20-30%0.5 uM-CRBNCRBN-WO2025162225A1PGDB_A008204PGDB_C024480PGDB_AS002133View
2D structure for PGDB_C024446
% Inhibition-=60-70%0.5 uM-CRBNCRBN-WO2025162225A1PGDB_A008301PGDB_C024446PGDB_AS002133View
2D structure for PGDB_C024373
% Inhibition-=40-53%0.5 uM-CRBNCRBN-WO2025162225A1PGDB_A009021PGDB_C024373PGDB_AS002133View
2D structure for PGDB_C024481
% Inhibition-=40-53%0.5 uM-CRBNCRBN-WO2025162225A1PGDB_A009111PGDB_C024481PGDB_AS002133View
2D structure for PGDB_C024514
% Inhibition-=40-53%0.5 uM-CRBNCRBN-WO2025162225A1PGDB_A009630PGDB_C024514PGDB_AS002133View
2D structure for PGDB_C024349
% Inhibition-=40-53%0.5 uM-CRBNCRBN-WO2025162225A1PGDB_A009817PGDB_C024349PGDB_AS002133View
2D structure for PGDB_C024522
% Inhibition-=70-80%0.5 uM-CRBNCRBN-WO2025162225A1PGDB_A009929PGDB_C024522PGDB_AS002133View
2D structure for PGDB_C024515
% Inhibition-=60-70%0.5 uM-CRBNCRBN-WO2025162225A1PGDB_A010383PGDB_C024515PGDB_AS002133View
2D structure for PGDB_C024472
% Inhibition-=40-53%0.5 uM-CRBNCRBN-WO2025162225A1PGDB_A010866PGDB_C024472PGDB_AS002133View
2D structure for PGDB_C024199
% Inhibition-=20-30%0.5 uM-CRBNCRBN-WO2025162225A1PGDB_A011908PGDB_C024199PGDB_AS002133View
2D structure for PGDB_C024447
% Inhibition-=40-53%0.5 uM-CRBNCRBN-WO2025162225A1PGDB_A012272PGDB_C024447PGDB_AS002133View
2D structure for PGDB_C024529
% Inhibition-=20-30%0.5 uM-CRBNCRBN-WO2025162225A1PGDB_A012535PGDB_C024529PGDB_AS002133View
2D structure for PGDB_C024280
% Inhibition-=10-20%0.5 uM-CRBNCRBN-WO2025162225A1PGDB_A012674PGDB_C024280PGDB_AS002133View
2D structure for PGDB_C024493
% Inhibition-=60-70%0.5 uM-CRBNCRBN-WO2025162225A1PGDB_A012681PGDB_C024493PGDB_AS002133View
2D structure for PGDB_C024443
% Inhibition-=53-60%0.5 uM-CRBNCRBN-WO2025162225A1PGDB_A013150PGDB_C024443PGDB_AS002133View
2D structure for PGDB_C024439
% Inhibition-=60-70%0.5 uM-CRBNCRBN-WO2025162225A1PGDB_A013176PGDB_C024439PGDB_AS002133View
2D structure for PGDB_C024338
% Inhibition-=40-53%0.5 uM-CRBNCRBN-WO2025162225A1PGDB_A013214PGDB_C024338PGDB_AS002133View
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