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Compound
PGDB_C024499
6 activity records1 related patents
2D structure
CC1(C)CCC(C(=O)N2CC3(CCN(Nc4ccc5c(c4)CN(C4CCC(=O)NC4=O)C5=O)CC3)C2)=C(c2ccc(F)cc2)C1Compound summary
Physicochemical properties
Activity compounds and values
Activity records
| Structure | Control | Value | Concentration | Time | Record ID | Compound | Assay | Details | |||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| % Inhibition | - | > | 30 | % | 0.1 uM | - | IKZF3 | - | - | WO2025162225A1 | PGDB_A021997 | PGDB_C024499 | PGDB_AS002324 | View |
| % Inhibition | - | > | 30 | % | 0.1 uM | - | IKZF3 | - | - | WO2025162225A1 | PGDB_A041599 | PGDB_C024499 | PGDB_AS000994 | View |
| % Inhibition | - | = | 10-20 | % | 10 nM | 96 h | IKZF3 | - | MV-4-11 | WO2025162225A1 | PGDB_A041739 | PGDB_C024499 | PGDB_AS001155 | View |
| % Inhibition | - | = | 40-50 | % | 500 nM | 96 h | IKZF3 | - | MV-4-11 | WO2025162225A1 | PGDB_A055599 | PGDB_C024499 | PGDB_AS001561 | View |
| % Inhibition | - | = | 80-100 | % | 2 uM | - | CRBN | CRBN | - | WO2025162225A1 | PGDB_A063653 | PGDB_C024499 | PGDB_AS002540 | View |
| % Inhibition | - | = | 60-70 | % | 0.5 uM | - | CRBN | CRBN | - | WO2025162225A1 | PGDB_A070279 | PGDB_C024499 | PGDB_AS002133 | View |